DRSC/TRiP Functional Genomics Resources

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Protein Alignment Agpat3 and AGPAT2

DIOPT Version :9

Sequence 1:NP_001246793.1 Gene:Agpat3 / 39820 FlyBaseID:FBgn0036623 Length:397 Species:Drosophila melanogaster
Sequence 2:NP_006403.2 Gene:AGPAT2 / 10555 HGNCID:325 Length:278 Species:Homo sapiens


Alignment Length:302 Identity:61/302 - (20%)
Similarity:98/302 - (32%) Gaps:104/302 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    38 CINFIQLLMHVFIKPIDKRLFRKLMYYACYSLYSQLIF-----------------------VSDW 79
            |:....||:.:.:     :|.|...:||..:||..|.|                       :..|
Human     6 CLAAALLLLLLLV-----QLSRAAEFYAKVALYCALCFTVSAVASLVCLLRHGGRTVENMSIIGW 65

  Fly    80 YAGSKMTVY---MDKEDFEKHAGKEHVLLIMNHKYEIDWLNGWMICEKLGVLGNCKAYAKKAIRY 141
            :..|....|   .:..|..:.......:::.||:..:|.:....:..:     .|...||:.:.:
Human    66 FVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLPE-----RCVQIAKRELLF 125

  Fly   142 VPIIGWGWWLAEFVFLNRN---------FDQDKTIITEQLKVVFSYPDPTWLLLNAEGTR----- 192
            :..:|...:|....|:||.         .|..:.::.|.|| |:.||         ||||     
Human   126 LGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENLK-VWIYP---------EGTRNDNGD 180

  Fly   193 FTPAK-------------------------HEASVKFAQERGMTVLKHHLIPRTKGFTASLAPIR 232
            ..|.|                         :....||.....:||.....|| |.|.||:..|  
Human   181 LLPFKKGAFYLAVQAQVPIVPVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIP-TSGLTAADVP-- 242

  Fly   233 GLCPVIYDINLAYRPT----DKTP----ATMLSLLHGKSVEP 266
               .::...:.|.|.|    .|||    ||.     |..|:|
Human   243 ---ALVDTCHRAMRTTFLHISKTPQENGATA-----GSGVQP 276

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Agpat3NP_001246793.1 PLN02380 23..387 CDD:178006 61/302 (20%)
LPLAT_LCLAT1-like 75..271 CDD:153252 51/265 (19%)
Acyltransf_C 258..336 CDD:292694 3/9 (33%)
AGPAT2NP_006403.2 LPLAT_AGPAT-like 67..249 CDD:153251 38/202 (19%)
HXXXXD motif. /evidence=ECO:0000250|UniProtKB:Q9D517 98..103 1/4 (25%)
EGTR motif. /evidence=ECO:0000305|PubMed:21873652 172..175 2/2 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0204
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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