DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Agpat4 and Lpcat4

DIOPT Version :9

Sequence 1:	NP_001261942.1	Gene:	Agpat4 / 39819	FlyBaseID:	FBgn0036622	Length:	380	Species:	Drosophila melanogaster
Sequence 2:	NP_997089.1	Gene:	Lpcat4 / 99010	MGIID:	2138993	Length:	524	Species:	Mus musculus

Alignment Length:	431	Identity:	74/431 - (17%)
Similarity:	115/431 - (26%)	Gaps:	203/431 - (47%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 GLGRLLIAVTFFTCGFFVNIGQLLLILLVRPFDKKLSRSLAYYL----HYSFY-------CIL-- 57
            ||.|||    ||..||          |.:|...::.||..|..|    |.:|:       |.|
Mouse    95 GLSRLL----FFLLGF----------LRIRVRGQRASRLEAPVLVAAPHSTFFDPIVLLPCDLPK 145

  Fly    58 ----------------------VCVAEWYAGSKLRVYIDPQDEQKFFGKEHGLLLMNHTYEIDWL 100
                                  :.|:.....|:.||..:.:......||              |.
Mouse   146 VVSRAENLSVPVIGALLRFNQAILVSRHDPASRRRVVEEVRRRATSGGK--------------WP 196

  Fly   101 TAWMITDKLGNLGGTKAYAKKMLRY--------VPV-------------LGWVW---------WM 135
            ......:      ||.:..|.:|::        |||             ..|.|         |:
Mouse   197 QVLFFPE------GTCSNKKALLKFKPGAFIAGVPVQPVLIRYPNSLDTTSWAWRGPGVLKVLWL 255

  Fly   136 ----------AEFIFLDRNFEKDKVVIKTQLKEVFSYPDPVWLLLNAEGTRFTPAKHELSVKFAE 190
                      .||:          .|.:..|:|   ..||.....|.:..            .|:
Mouse   256 TASQPCSIVDVEFL----------PVYQPSLEE---SKDPTLYANNVQRV------------MAQ 295

  Fly   191 ERGLPLLKHHLIPRTKGFTTSLPTM----------------------RGICPAIYDINLAFKKNA 233
            ..|:|..:..       |..|||.:                      .|:.|...|:      .|
Mouse   296 ALGIPATECE-------FVGSLPVIVVGQLKVALEPQLWELAKVLQKAGLSPGFVDM------GA 347

  Fly   234 EP-KPTMLSQLNGEPVEPYMYIRRVPLDVVPDDEKEAAAWMQDFFAEKDKIIDSFHETG------ 291
            || :..|:||        ..:.:::.|.   |.:..|.|:  .:|.:..|.:..|....
Mouse   348 EPGRSRMISQ--------EAFAQQLQLS---DPQTVAGAF--SYFQQDAKGLVDFRNVALALAAL 399

  Fly   292 --------------SFFKNSGVKEVPEKIYKPRLSTLLNFL 318
                          ..|.....:.....:||...||:|:.|
Mouse   400 DGGRSLEELTRLAFELFAEEQAEGSDRLLYKDGFSTILHLL 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Agpat4	NP_001261942.1	PLN02380	12..366	CDD:178006	69/425 (16%)
		LPLAT_LCLAT1-like	58..255	CDD:153252	41/259 (16%)
		Acyltransf_C	243..320	CDD:292694	14/96 (15%)
Lpcat4	NP_997089.1	LPLAT_LPCAT1-like	109..306	CDD:153253	37/248 (15%)
		PlsC	109..295	CDD:223282	34/230 (15%)
		HXXXXD motif	129..134		2/4 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	490..524
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900