DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Agpat4 and GPAT3

DIOPT Version :9

Sequence 1:	NP_001261942.1	Gene:	Agpat4 / 39819	FlyBaseID:	FBgn0036622	Length:	380	Species:	Drosophila melanogaster
Sequence 2:	XP_016864269.1	Gene:	GPAT3 / 84803	HGNCID:	28157	Length:	526	Species:	Homo sapiens

Alignment Length:	181	Identity:	45/181 - (24%)
Similarity:	74/181 - (40%)	Gaps:	53/181 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 GLGRLLIAVTFFTCGFFVNIGQLLLILLVRPFDKKLSRSLAYYLHYSFYCILVCVAE-----WYA 65
            |:..|:|..|.        :|||       | |..|...|:..:|.:  |..:||..     .|.
Human   259 GISLLVIGTTL--------VGQL-------P-DSSLKNWLSELVHLT--CCRICVRALSGTIHYH 305

  Fly    66 GSKLRVYIDPQDEQKFFGKEHGLLLMNHTYEIDWLTAWMITD----KLGNL-GGTKAYAKK-MLR 124
            ..:.|    ||        :.|:.:.|||..||.|.  :.||    .:|.: ||.....:: |::
Human   306 NKQYR----PQ--------KGGICVANHTSPIDVLI--LTTDGCYAMVGQVHGGLMGIIQRAMVK 356

  Fly   125 YVPVLGWVWWMAEFIFLDRNFEKDKVVIKTQLKEVFSYPDPVWLLLNAEGT 175
            ..|   .||:       :|:..||:.::..:|||..:....:.:|:..|||
Human   357 ACP---HVWF-------ERSEMKDRHLVTKRLKEHIADKKKLPILIFPEGT 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Agpat4	NP_001261942.1	PLN02380	12..366	CDD:178006	43/175 (25%)
		LPLAT_LCLAT1-like	58..255	CDD:153252	32/129 (25%)
		Acyltransf_C	243..320	CDD:292694
GPAT3	XP_016864269.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900