DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Agpat4 and LPAT2

DIOPT Version :9

Sequence 1:	NP_001261942.1	Gene:	Agpat4 / 39819	FlyBaseID:	FBgn0036622	Length:	380	Species:	Drosophila melanogaster
Sequence 2:	NP_567052.1	Gene:	LPAT2 / 824934	AraportID:	AT3G57650	Length:	389	Species:	Arabidopsis thaliana

Alignment Length:	369	Identity:	120/369 - (32%)
Similarity:	206/369 - (55%)	Gaps:	10/369 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 IAVTFFTCGFFVNIGQLLLILLVRPFDKKLSRSLAYYLHYSFYCILVCVAEWYAGSKLRVYIDPQ 76
            :.:.||..|..||:.|.:..:|:||..|...|.:...:..:.:..||.:.:|:||.|::|:.|.:
plant    11 LGLLFFISGLAVNLFQAVCYVLIRPLSKNTYRKINRVVAETLWLELVWIVDWWAGVKIQVFADNE 75

  Fly    77 DEQKFFGKEHGLLLMNHTYEIDWLTAWMITDKLGNLGGTKAYAKKMLRYVPVLGWVWWMAEFIFL 141
            ...: .||||.|::.||..:||||..|::..:.|.||...|..||..:::||:||..|.:|::||
plant    76 TFNR-MGKEHALVVCNHRSDIDWLVGWILAQRSGCLGSALAVMKKSSKFLPVIGWSMWFSEYLFL 139

  Fly   142 DRNFEKDKVVIKTQLKEVFSYPDPVWLLLNAEGTRFTPAKHELSVKFAEERGLPLLKHHLIPRTK 206
            :||:.||:..:|:.|:.:..:|.|.||.|..||||||.||.:.:.::|....||:.::.||||||
plant   140 ERNWAKDESTLKSGLQRLSDFPRPFWLALFVEGTRFTEAKLKAAQEYAASSELPIPRNVLIPRTK 204

  Fly   207 GFTTSLPTMRGICPAIYDINLAFKKNAEPKPTMLSQLNGEPVEPYMYIRRVPLDVVPDDEKEAAA 271
            ||.:::..||...|||||:.:...|.: |.||||....|:|...:::|:...:..:|:.:...|.
plant   205 GFVSAVSNMRSFVPAIYDMTVTIPKTS-PPPTMLRLFKGQPSVVHVHIKCHSMKDLPESDDAIAQ 268

  Fly   272 WMQDFFAEKDKIIDSFHETGSFFKNSGVKEVPEKIYKPRLSTLLNFLGWATFAVLCILHYLVTSL 336
            |.:|.|..||.::|......:|   .|.:|  :.|.:| :.:|...|.||....|..:.:|..:.
plant   269 WCRDQFVAKDALLDKHIAADTF---PGQQE--QNIGRP-IKSLAVVLSWACVLTLGAIKFLHWAQ 327

  Fly   337 VAGNWFGFITVLSILGGFYSL-MEYAVNASKISKASAYGAAAAK 379
            :..:|.| ||:.::..|..:| |:..:.:|:..:::......||
plant   328 LFSSWKG-ITISALGLGIITLCMQILIRSSQSERSTPAKVVPAK 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Agpat4	NP_001261942.1	PLN02380	12..366	CDD:178006	117/354 (33%)
		LPLAT_LCLAT1-like	58..255	CDD:153252	78/196 (40%)
		Acyltransf_C	243..320	CDD:292694	18/76 (24%)
LPAT2	NP_567052.1	PLN02380	1..375	CDD:178006	120/369 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	112	1.000	Domainoid score	I2059
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10591
Inparanoid	1	1.050	223	1.000	Inparanoid score	I1184
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D959325at2759
OrthoFinder	1	1.000	-	-		FOG0001449
OrthoInspector	1	1.000	-	-		mtm1207
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10983
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1337
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.930