DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Agpat4 and LPAT5

DIOPT Version :9

Sequence 1:	NP_001261942.1	Gene:	Agpat4 / 39819	FlyBaseID:	FBgn0036622	Length:	380	Species:	Drosophila melanogaster
Sequence 2:	NP_001030724.2	Gene:	LPAT5 / 821418	AraportID:	AT3G18850	Length:	375	Species:	Arabidopsis thaliana

Alignment Length:	393	Identity:	114/393 - (29%)
Similarity:	184/393 - (46%)	Gaps:	67/393 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LRGLGRLLIAVT--FFTCGFFVNIGQLLLILLVRPFDKKLSRSLAYYLHYSFYCILVCVAEWYA- 65
            |||:..|::.|:  |....|:..:..::|.|              :.:.||..|:......|.|
plant    18 LRGIICLMVLVSTAFMMLIFWGFLSAVVLRL--------------FSIRYSRKCVSFFFGSWLAL 68

  Fly    66 -------GSKLRVYIDPQDEQKFFG-----KEHGLLLMNHTYEIDWLTAWMITDKLGNLGGTKAY 118
                   .:|.:|.        |.|     ::..||:.||..|:||:..|.:..:.|.:|..|..
plant    69 WPFLFEKINKTKVI--------FSGDKVPCEDRVLLIANHRTEVDWMYFWDLALRKGQIGNIKYV 125

  Fly   119 AKKMLRYVPVLGWVWWMAEFIFLDRNFEKDKVVIKTQLKEVFSYP-DPVWLLLNAEGTRFTPAKH 182
            .|..|..:|:.||.:.:.|||.::|.:|.|:..:: |:...|..| |.:||.|..|||.:|.||.
plant   126 LKSSLMKLPLFGWAFHLFEFIPVERRWEVDEANLR-QIVSSFKDPRDALWLALFPEGTDYTEAKC 189

  Fly   183 ELSVKFAEERGLPLLKHHLIPRTKGFTTSLPTMRGICPAIYDINLAFKKNAEPKPTMLSQLNG-E 246
            :.|.|||.|.|||:|.:.|:||||||.:.|..:.....|:||:.:.:|...   |:.|..:.| |
plant   190 QRSKKFAAENGLPILNNVLLPRTKGFVSCLQELSCSLDAVYDVTIGYKTRC---PSFLDNVYGIE 251

  Fly   247 PVEPYMYIRRVPLDVVPDDEKEAAAWMQDFFAEKDKIIDSFHETGSFFKNSGVKEVPEKIYKPRL 311
            |.|.:::|||:.|..:|:.||:..||:.:.|..||::::.|:..|.|......||...|.|
plant   252 PSEVHIHIRRINLTQIPNQEKDINAWLMNTFQLKDQLLNDFYSNGHFPNEGTEKEFNTKKY---- 312

  Fly   312 STLLNFLGWATFAVLCILHYLVTSLVAGNWFGFITVLSILGGFY------------SLMEYAVNA 364
              |:|.|....|..:|......:|::   ||.....|:.:   |            .|:|.|.|:
plant   313 --LINCLAVIAFTTICTHLTFFSSMI---WFRIYVSLACV---YLTSATHFNLRSVPLVETAKNS 369

  Fly   365 SKI 367
            .|:
plant   370 LKL 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Agpat4	NP_001261942.1	PLN02380	12..366	CDD:178006	109/382 (29%)
		LPLAT_LCLAT1-like	58..255	CDD:153252	68/211 (32%)
		Acyltransf_C	243..320	CDD:292694	26/77 (34%)
LPAT5	NP_001030724.2	PLN02510	1..375	CDD:178126	114/393 (29%)
		LPLAT_LCLAT1-like	70..260	CDD:153252	66/201 (33%)
		Acyltransf_C	251..315	CDD:292694	23/69 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	112	1.000	Domainoid score	I2059
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D959325at2759
OrthoFinder	1	1.000	-	-		FOG0001449
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102498
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.720