DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Agpat4 and LPCAT1

DIOPT Version :9

Sequence 1:	NP_001261942.1	Gene:	Agpat4 / 39819	FlyBaseID:	FBgn0036622	Length:	380	Species:	Drosophila melanogaster
Sequence 2:	XP_011512434.1	Gene:	LPCAT1 / 79888	HGNCID:	25718	Length:	571	Species:	Homo sapiens

Alignment Length:	117	Identity:	25/117 - (21%)
Similarity:	46/117 - (39%)	Gaps:	17/117 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 WYAGSKLRVYIDPQDEQKFFGKEHGLLLMNHTYEIDWLTAWMITDKLGNLGGTKAYAKKMLRYVP 127
            |:||...||.:  :..|....:...|.|..|:...|.:...|....:        ..|...|.:|
Human   144 WFAGGFHRVAV--KGRQALPTEAAILTLAPHSSYFDAIPVTMTMSSI--------VMKAESRDIP 198

  Fly   128 VLGWVWWMAEFIFLDRNFE--KDKVV--IKTQLKEVFSYPDPVWLLLNAEGT 175
            :.|.:......:|:.|:.:  :.|.|  ||.:.:....:|.   :::..|||
Human   199 IWGTLIQYIRPVFVSRSDQDSRRKTVEEIKRRAQSNGKWPQ---IMIFPEGT 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Agpat4	NP_001261942.1	PLN02380	12..366	CDD:178006	25/117 (21%)
		LPLAT_LCLAT1-like	58..255	CDD:153252	25/117 (21%)
		Acyltransf_C	243..320	CDD:292694
LPCAT1	XP_011512434.1	PlsC	95..>279	CDD:223282	25/117 (21%)
		LPLAT_LPCAT1-like	140..351	CDD:153253	25/117 (21%)
		EF-hand_7	458..516	CDD:290234
		EF-hand_8	469..520	CDD:290545
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900