DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Agpat4 and Agpat4

DIOPT Version :9

Sequence 1:	NP_001261942.1	Gene:	Agpat4 / 39819	FlyBaseID:	FBgn0036622	Length:	380	Species:	Drosophila melanogaster
Sequence 2:	XP_006523408.3	Gene:	Agpat4 / 68262	MGIID:	1915512	Length:	458	Species:	Mus musculus

Alignment Length:	373	Identity:	132/373 - (35%)
Similarity:	217/373 - (58%)	Gaps:	21/373 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LGRLLIAVTFFTCGFFVNIGQLLLILLVRPFDKKLSRSLAYYLHYSFYCILVCVAEWYAGSKLRV 71
            |..|:....|...|..||..| |..|::.|.:|:|.|.:...|.|.....||.:.||::|::..:
Mouse    92 LCHLVFCYVFIASGLIVNAIQ-LCTLVIWPINKQLFRKINARLCYCVSSQLVMLLEWWSGTECTI 155

  Fly    72 YIDPQDEQKFFGKEHGLLLMNHTYEIDWLTAWMITDKLGNLGGTKAYAKKMLRYVPVLGWVWWMA 136
            |.||: ....:|||:.::::||.:|||:|..|.:.::||.||.:|..|||.|.|||::||:|:..
Mouse   156 YTDPK-ACPHYGKENAIVVLNHKFEIDFLCGWSLAERLGILGNSKVLAKKELAYVPIIGWMWYFV 219

  Fly   137 EFIFLDRNFEKDKVVIKTQLKEVFSYPDPVWLLLNAEGTRFTPAKHELSVKFAEERGLPLLKHHL 201
            |.||..|.:|:|:..:...|..:..||:....|::.||||||..||::|::.|:.:|||.|||||
Mouse   220 EMIFCTRKWEQDRQTVAKSLLHLRDYPEKYLFLIHCEGTRFTEKKHQISMQVAQAKGLPSLKHHL 284

  Fly   202 IPRTKGFTTSLPTMRGICPAIYDINLAFKKNAEPKPTMLSQLNGEPVEPYMYIRRVPLDVVPDDE 266
            :||||||..::..:|.:.||:||..|.|:.|  ..||:|..|||:......|:||:|::.:|:||
Mouse   285 LPRTKGFAITVKCLRDVVPAVYDCTLNFRNN--ENPTLLGVLNGKKYHADCYVRRIPMEDIPEDE 347

  Fly   267 KEAAAWMQDFFAEKDKIIDSFHETGSFFKNSGVKEVPEKIYKP--RLSTLLNFLGWATFAVLCIL 329
            .:.:||:...:.|||...:.::.||.|         ||..:.|  |..:|:|:|.||:..:....
Mouse   348 DKCSAWLHKLYQEKDAFQEEYYRTGVF---------PETPWVPPRRPWSLVNWLFWASLLLYPFF 403

  Fly   330 HYLVTSLVAGNWFGFITVLSILGGFYSL---MEYAVNASKISKASAYG 374
            .:||:.:.:|:   .:|:.|::..|...   :.:.:..::|.|.||||
Mouse   404 QFLVSMVSSGS---SVTLASLVLIFCMASMGVRWMIGVTEIDKGSAYG 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Agpat4	NP_001261942.1	PLN02380	12..366	CDD:178006	124/358 (35%)
		LPLAT_LCLAT1-like	58..255	CDD:153252	81/196 (41%)
		Acyltransf_C	243..320	CDD:292694	25/78 (32%)
Agpat4	XP_006523408.3	PLN02380	100..406	CDD:178006	116/307 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167848227
Domainoid	1	1.000	125	1.000	Domainoid score	I5440
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	289	1.000	Inparanoid score	I2791
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG51956
OrthoDB	1	1.010	-	-		D482283at33208
OrthoFinder	1	1.000	-	-		FOG0001449
OrthoInspector	1	1.000	-	-		mtm8818
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10983
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3473
SonicParanoid	1	1.000	-	-		X1337
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.900