DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Agpat4 and Aup1

DIOPT Version :9

Sequence 1:	NP_001261942.1	Gene:	Agpat4 / 39819	FlyBaseID:	FBgn0036622	Length:	380	Species:	Drosophila melanogaster
Sequence 2:	NP_001073368.1	Gene:	Aup1 / 680423	RGDID:	1591777	Length:	410	Species:	Rattus norvegicus

Alignment Length:	163	Identity:	36/163 - (22%)
Similarity:	53/163 - (32%)	Gaps:	37/163 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 LLLILLVRPFDKKLSRSLAYYLHYSFYCILVCVAEWYAGSKLRVY-----------IDPQDEQKF 81
            ||.:||..|....|   |...|....:..||..|  ...|.||.:           :..|::...
  Rat    25 LLALLLYAPVGLCL---LVLRLFLGLHVFLVSCA--LPDSVLRRFVVRTMCAVLGLVARQEDSGL 84

  Fly    82 FGKEHGLLLMNHTYEIDWLTAWMITDKLGNLGGTKAYAKKMLRYVPVLGWVWWMAEFIFLDRNFE 146
            ......:|:.||....|.....::|          ..:..:|...|  .:|.|...|:.:||..|
  Rat    85 RDHRVRVLISNHVTPFDHNIVNLLT----------TCSTPLLNSPP--SFVCWSRGFMEMDRRVE 137

  Fly   147 ----KDKVVIKTQLKEVFSYPDPVWLLLNAEGT 175
                ..|....|:|.     |.|:.|....|.|
  Rat   138 LVESLKKFCASTRLP-----PTPLLLFPEEEAT 165

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Agpat4	NP_001261942.1	PLN02380	12..366	CDD:178006	36/163 (22%)
		LPLAT_LCLAT1-like	58..255	CDD:153252	27/133 (20%)
		Acyltransf_C	243..320	CDD:292694
Aup1	NP_001073368.1	LPLAT	66..264	CDD:302626	22/117 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	259..293
		CUE_AUP1	300..340	CDD:270603
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	348..367
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900