DRSC/TRiP Functional Genomics Resources

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Protein Alignment Agpat4 and Agpat2

DIOPT Version :9

Sequence 1:NP_001261942.1 Gene:Agpat4 / 39819 FlyBaseID:FBgn0036622 Length:380 Species:Drosophila melanogaster
Sequence 2:NP_080488.1 Gene:Agpat2 / 67512 MGIID:1914762 Length:278 Species:Mus musculus


Alignment Length:322 Identity:67/322 - (20%)
Similarity:115/322 - (35%) Gaps:110/322 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    28 LLLILLVRPFDKKLSRSLAYYLHYSFYCIL----------VC-------------VAEWYAGSKL 69
            |||:|||     :|||:..:|.....||:|          ||             :..|:..|..
Mouse    12 LLLLLLV-----QLSRTARFYAKVGLYCVLCLSFSAAASIVCLLRHGGRTVDNMSIISWFVRSFK 71

  Fly    70 RVY---IDPQDEQKFFGKEHGLLLMNHTYEIDWLTAWMITDKLGNLGGTKAYAKKMLRYVPVLGW 131
            .||   .:...::|.......:::.||...:|.:....|..|     .....||:.|.:...:|.
Mouse    72 YVYGLRFEVSGQKKLEVDGPCVIISNHQSILDMMGLMEILPK-----RCVQIAKRELMFTGPVGL 131

  Fly   132 VWWMAEFIFLDRN---------FEKDKVVIKTQLKEVFSYPDPVWLLLNAEGTRFTPAKHELSVK 187
            :.::....|::|.         .:...:::|..|| |:.||         ||||           
Mouse   132 IMYLGGVYFINRQQARTAMSVMADLGDLMVKENLK-VWIYP---------EGTR----------- 175

  Fly   188 FAEERGLPLLKHHLIPRTKG-FTTSLPTMRGICPAIYDINLAF---KKNAEPKPTMLSQLNGEPV 248
              .:.|      .|:|..|| |..::.....|.|.:|....:|   |.......|:..|:     
Mouse   176 --NDNG------DLLPFKKGAFYLAIQAQVPIIPVVYSSFSSFYNVKTKLFTSGTIKVQV----- 227

  Fly   249 EPYMYIRRVPLDVVPDDEKEAAAWMQDFFAEKDKIIDSFHET--GSFF-------KNSGVKE 301
                      ||.||.:      .:.|  |:..|::|:.:::  .:|.       :||.:||
Mouse   228 ----------LDAVPTN------GLTD--ADVTKLVDTCYQSMRATFLQISQIPQENSAIKE 271

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Agpat4NP_001261942.1 PLN02380 12..366 CDD:178006 67/322 (21%)
LPLAT_LCLAT1-like 58..255 CDD:153252 41/225 (18%)
Acyltransf_C 243..320 CDD:292694 13/68 (19%)
Agpat2NP_080488.1 PlsC 30..259 CDD:223282 53/285 (19%)
LPLAT_AGPAT-like 67..240 CDD:153251 43/229 (19%)
HXXXXD motif. /evidence=ECO:0000250|UniProtKB:Q9D517 98..103 1/4 (25%)
EGTR motif. /evidence=ECO:0000250|UniProtKB:O15120 172..175 2/2 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0204
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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