DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Agpat4 and Agpat3

DIOPT Version :9

Sequence 1:	NP_001261942.1	Gene:	Agpat4 / 39819	FlyBaseID:	FBgn0036622	Length:	380	Species:	Drosophila melanogaster
Sequence 2:	NP_001246793.1	Gene:	Agpat3 / 39820	FlyBaseID:	FBgn0036623	Length:	397	Species:	Drosophila melanogaster

Alignment Length:	376	Identity:	233/376 - (61%)
Similarity:	294/376 - (78%)	Gaps:	1/376 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSHLRGLGRLLIAVTFFTCGFFVNIGQLLLILLVRPFDKKLSRSLAYYLHYSFYCILVCVAEWYA 65
            :..|| |..|.||:||||.|..:|..|||:.:.::|.||:|.|.|.||..||.|..|:.|::|||
  Fly    18 LKQLR-LIHLCIALTFFTSGLCINFIQLLMHVFIKPIDKRLFRKLMYYACYSLYSQLIFVSDWYA 81

  Fly    66 GSKLRVYIDPQDEQKFFGKEHGLLLMNHTYEIDWLTAWMITDKLGNLGGTKAYAKKMLRYVPVLG 130
            |||:.||:|.:|.:|..||||.||:|||.||||||..|||.:|||.||..||||||.:||||::|
  Fly    82 GSKMTVYMDKEDFEKHAGKEHVLLIMNHKYEIDWLNGWMICEKLGVLGNCKAYAKKAIRYVPIIG 146

  Fly   131 WVWWMAEFIFLDRNFEKDKVVIKTQLKEVFSYPDPVWLLLNAEGTRFTPAKHELSVKFAEERGLP 195
            |.||:|||:||:|||::||.:|..|||.|||||||.|||||||||||||||||.|||||:|||:.
  Fly   147 WGWWLAEFVFLNRNFDQDKTIITEQLKVVFSYPDPTWLLLNAEGTRFTPAKHEASVKFAQERGMT 211

  Fly   196 LLKHHLIPRTKGFTTSLPTMRGICPAIYDINLAFKKNAEPKPTMLSQLNGEPVEPYMYIRRVPLD 260
            :|||||||||||||.||..:||:||.|||||||::...:...||||.|:|:.|||::.:||:||:
  Fly   212 VLKHHLIPRTKGFTASLAPIRGLCPVIYDINLAYRPTDKTPATMLSLLHGKSVEPHLLMRRIPLE 276

  Fly   261 VVPDDEKEAAAWMQDFFAEKDKIIDSFHETGSFFKNSGVKEVPEKIYKPRLSTLLNFLGWATFAV 325
            .||:||||||||:|:.|.|||||||||.|||||||.||:||||..:.|.||.:|:||:.||.|::
  Fly   277 QVPEDEKEAAAWLQNLFVEKDKIIDSFLETGSFFKTSGIKEVPAYVNKRRLCSLVNFVCWAVFSL 341

  Fly   326 LCILHYLVTSLVAGNWFGFITVLSILGGFYSLMEYAVNASKISKASAYGAA 376
            .||.:|::|||:|.||..|||.||:||.||.||..|:|.::|||||.||::
  Fly   342 SCIFYYVITSLLAANWTAFITALSVLGLFYWLMGQAINKTQISKASNYGSS 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Agpat4	NP_001261942.1	PLN02380	12..366	CDD:178006	222/353 (63%)
		LPLAT_LCLAT1-like	58..255	CDD:153252	130/196 (66%)
		Acyltransf_C	243..320	CDD:292694	49/76 (64%)
Agpat3	NP_001246793.1	PLN02380	23..387	CDD:178006	227/363 (63%)
		LPLAT_LCLAT1-like	75..271	CDD:153252	130/195 (67%)
		Acyltransf_C	258..336	CDD:292694	49/77 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467245
Domainoid	1	1.000	112	1.000	Domainoid score	I2059
eggNOG	1	0.900	-	-		E1_COG0204
Homologene	1	1.000	-	-		H10591
Inparanoid	1	1.050	223	1.000	Inparanoid score	I1184
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D482283at33208
OrthoFinder	1	1.000	-	-		FOG0001449
OrthoInspector	1	1.000	-	-		mtm6533
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10983
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3473
SonicParanoid	1	1.000	-	-		X1337
	12	11.930