DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Agpat4 and aup1

DIOPT Version :9

Sequence 1:	NP_001261942.1	Gene:	Agpat4 / 39819	FlyBaseID:	FBgn0036622	Length:	380	Species:	Drosophila melanogaster
Sequence 2:	XP_005173140.1	Gene:	aup1 / 324654	ZFINID:	ZDB-GENE-030131-3375	Length:	429	Species:	Danio rerio

Alignment Length:	289	Identity:	62/289 - (21%)
Similarity:	106/289 - (36%)	Gaps:	66/289 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LLIAVTFFTCGFFVNIGQLLLILLVRPFDKKLSRSLAYYLHYSFYCILVCVAEWYAGSKLRVYID 74
            ||:.:.:...||.:    :||.:.:......:|.:|...:...|...::|       |.|.:::.
Zfish    22 LLLLLLYAPVGFCL----MLLRIFIGVHVFLVSCALPDSIVRRFIVRIMC-------SVLGLHVQ 75

  Fly    75 PQDEQKFFGKEHGLLLMNHTYEIDWLTAWMITDKLGNLGGTKAYAKKMLRYVPVLGWVWWMAEFI 139
             |:..:...|...|.:.||....|.....::|.           ....|...|| |::.|...|:
Zfish    76 -QNSPRLRDKTTRLYVCNHVTHFDHNIINLLTS-----------CNTPLLEGPV-GFLCWARGFM 127

  Fly   140 FLDRNFEKDKVVIKTQLKEVF----SYPDPVWLLLNAEGTRFTPAKHELSVKFAEE---RG-LPL 196
            .|.:.     |..:|:|.|..    |.||.:.|||                 |.||   .| ..|
Zfish   128 ELGQG-----VGSRTELTETLHRYCSSPDTLPLLL-----------------FPEEDTTNGRTGL 170

  Fly   197 LKHHLIPRTKGFTTSLPTMRGICPAIYDINLAFKKNAEPKPTMLSQLNGEPVEPY--MYIRRVPL 259
            ||....|    |:.|    ..|.|....:...|...:.|:.:.|::|......|:  .::|.:|.
Zfish   171 LKFSSWP----FSVS----DSIQPVALLVKRPFIAVSTPESSWLTELLWTFFVPFTVYHVRWLPP 227

  Fly   260 DVVPDDE--KEAAAWMQDFFAEKDKIIDS 286
            ....|.|  :|.|:.:|...|.:..:|.:
Zfish   228 LSKEDGETHQEFASKVQGLLATELGVIST 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Agpat4	NP_001261942.1	PLN02380	12..366	CDD:178006	60/287 (21%)
		LPLAT_LCLAT1-like	58..255	CDD:153252	44/206 (21%)
		Acyltransf_C	243..320	CDD:292694	11/48 (23%)
aup1	XP_005173140.1	LPLAT	63..263	CDD:302626	53/244 (22%)
aup1	XP_005173140.1	CUE_AUP1	310..354	CDD:270603
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900