DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Agpat4 and Agpat3

DIOPT Version :9

Sequence 1:	NP_001261942.1	Gene:	Agpat4 / 39819	FlyBaseID:	FBgn0036622	Length:	380	Species:	Drosophila melanogaster
Sequence 2:	NP_001099848.1	Gene:	Agpat3 / 294324	RGDID:	1305787	Length:	376	Species:	Rattus norvegicus

Alignment Length:	373	Identity:	138/373 - (36%)
Similarity:	212/373 - (56%)	Gaps:	15/373 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LLIAVTFFTCGFFVNIGQLLLILLVRPFDKKLSRSLAYYLHYSFYCILVCVAEWYAGSKLRVYID 74
            |||...|...|..:|..||..:.| .|..|.|.|.:...|.||.:..||.:.||::.::..::.|
  Rat    15 LLIGFVFVVSGLIINFTQLCTLAL-WPISKNLYRRINCRLAYSLWSQLVMLLEWWSCTECTLFTD 78

  Fly    75 PQDEQKFFGKEHGLLLMNHTYEIDWLTAWMITDKLGNLGGTKAYAKKMLRYVPVLGWVWWMAEFI 139
             |.....|||||.::::||.:|||:|..|.:.::.|.||.:|..||:.|.|||::||.|:..|.:
  Rat    79 -QATVNHFGKEHVVVILNHNFEIDFLCGWTMCERFGVLGSSKVLAKRELLYVPLIGWTWYFLEIV 142

  Fly   140 FLDRNFEKDKVVIKTQLKEVFSYPDPVWLLLNAEGTRFTPAKHELSVKFAEERGLPLLKHHLIPR 204
            |..|.:|:|:..:...|:.:.:||:.:|.||..||||||..||.:|::.|..:|||.||:||:||
  Rat   143 FCKRKWEEDRDTVIEGLRRLANYPEYMWFLLYCEGTRFTETKHRVSMEVAASKGLPPLKYHLLPR 207

  Fly   205 TKGFTTSLPTMRGICPAIYDINLAFKKNAEPKPTMLSQLNGEPVEPYMYIRRVPLDVVPDDEKEA 269
            ||||||::..:||...||||:.|.|:.|  ..|::|..|.|:..|..|.:||.||:.:|.||..|
  Rat   208 TKGFTTAVQCLRGTVAAIYDVTLNFRGN--KNPSLLGILYGKKYEADMCVRRFPLEDIPADETGA 270

  Fly   270 AAWMQDFFAEKDKIIDSFHETGSFFKNSGVKEVPEKIYKP--RLSTLLNFLGWATFAVLCILHYL 332
            |.|:...:.|||.:.:.:.::|.|         |.:..||  |..||||||.||||.:..:..::
  Rat   271 AQWLHKLYQEKDALQEMYKQSGVF---------PGEQIKPARRPWTLLNFLCWATFLLSPLFSFV 326

  Fly   333 VTSLVAGNWFGFITVLSILGGFYSLMEYAVNASKISKASAYGAAAAKK 380
            :....:|:....:|.|..:|.....:...:..::|.|.|:||....||
  Rat   327 LGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQELKK 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Agpat4	NP_001261942.1	PLN02380	12..366	CDD:178006	129/355 (36%)
		LPLAT_LCLAT1-like	58..255	CDD:153252	81/196 (41%)
		Acyltransf_C	243..320	CDD:292694	29/78 (37%)
Agpat3	NP_001099848.1	PLN02380	12..325	CDD:178006	127/322 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351806
Domainoid	1	1.000	129	1.000	Domainoid score	I5116
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10591
Inparanoid	1	1.050	295	1.000	Inparanoid score	I2662
OMA	1	1.010	-	-		QHG51956
OrthoDB	1	1.010	-	-		D482283at33208
OrthoFinder	1	1.000	-	-		FOG0001449
OrthoInspector	1	1.000	-	-		mtm9064
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10983
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1337
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.870