DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Agpat4 and Lpcat1

DIOPT Version :9

Sequence 1:	NP_001261942.1	Gene:	Agpat4 / 39819	FlyBaseID:	FBgn0036622	Length:	380	Species:	Drosophila melanogaster
Sequence 2:	NP_663351.3	Gene:	Lpcat1 / 210992	MGIID:	2384812	Length:	534	Species:	Mus musculus

Alignment Length:	181	Identity:	38/181 - (20%)
Similarity:	65/181 - (35%)	Gaps:	41/181 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 RLLIAVTFFTCGFFVNIGQLLLILLVRPF---------DKKLSRSLAYYLH-YSFYCILVCVAEW 63
            |||.|.              .::||..||         ||:..:.||.:.. ..|....:....|
Mouse    57 RLLFAA--------------FMMLLAWPFALLASLGPPDKEPEQPLALWRKVVDFLLKAIMRTMW 107

  Fly    64 YAGSKLRVYIDPQDEQKFFGKEHGLLLMNHTYEIDWLTAWMITDKLGNLGGTKAYAKKMLRYVPV 128
            :||...||.:  :..|....:...|.|..|:...|.:...|....:        ..|...|.:|:
Mouse   108 FAGGFHRVAV--KGRQALPTEAAILTLAPHSSYFDAIPVTMTMSSI--------VMKAESRDIPI 162

  Fly   129 LGWVWWMAEFIFLDRNFE--KDKVV--IKTQLKEVFSYPDPVWLLLNAEGT 175
            .|.:......:|:.|:.:  :.|.|  ||.:.:....:|.   :::..|||
Mouse   163 WGTLIRYIRPVFVSRSDQDSRRKTVEEIKRRAQSNGKWPQ---IMIFPEGT 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Agpat4	NP_001261942.1	PLN02380	12..366	CDD:178006	35/178 (20%)
		LPLAT_LCLAT1-like	58..255	CDD:153252	25/122 (20%)
		Acyltransf_C	243..320	CDD:292694
Lpcat1	NP_663351.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..25
		PlsC	59..>242	CDD:223282	36/179 (20%)
		LPLAT_LPCAT1-like	103..314	CDD:153253	25/121 (21%)
		HXXXXD motif. /evidence=ECO:0000269\|PubMed:18285344	135..140		1/4 (25%)
		EFh	384..437	CDD:298682
		EF-hand_7	421..479	CDD:290234
		EF-hand_8	432..483	CDD:290545
		Di-lysine motif. /evidence=ECO:0000305\|PubMed:16704971	531..534
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900