DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Agpat4 and acl-11

DIOPT Version :9

Sequence 1:	NP_001261942.1	Gene:	Agpat4 / 39819	FlyBaseID:	FBgn0036622	Length:	380	Species:	Drosophila melanogaster
Sequence 2:	NP_491479.2	Gene:	acl-11 / 185044	WormBaseID:	WBGene00017888	Length:	368	Species:	Caenorhabditis elegans

Alignment Length:	302	Identity:	80/302 - (26%)
Similarity:	146/302 - (48%)	Gaps:	30/302 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LIAVTFFTCGFFVNIGQLLLILLVRPFDKKLSRSLAYYLHYSFYCILVCVAEWYAGSKLRVYIDP 75
            |..|.|.:|.  :.||.:..|:     .:.:::.|...|:.|:..:.:.|.|..:|  :.:|:..
Worm    23 LSMVPFASCA--IVIGGVSWIV-----PRHVAQQLDNMLYKSYMRLCLFVFENLSG--VEIYLHG 78

  Fly    76 QDEQ---KFFGKEHGLLLMNHTYEIDWLTAWMITDKLGNLGGTKAY---AKKMLRYVPVLGWVWW 134
            .:|:   |....|:.:::.||...:||:...|:..:.|:.|..:|:   .|..:..||:.||..:
Worm    79 TNEEVVNKTGKPENAVMISNHQSNVDWIIPVMLAARHGDQGNEQAFRVMVKNSIHLVPMFGWYIF 143

  Fly   135 MAEFIFLDRNFEKDKVVIKTQLKEVFSYPDPVWLLLNAEGTRFTPAKHEL---SVKFAEERGLPL 196
            ...:|::.|..|.....:..|||.:.....|.|||:..||||.:..|..|   |.:|.|:.|...
Worm   144 QHGYIYVRRFGEFIGAPVLRQLKWLNESDPPYWLLIFPEGTRNSAKKKHLLESSNRFLEKSGRQP 208

  Fly   197 LKHHLIPRTKGFTTSLPTMRGICPAIYDINLAF--KKNAEPK---PTMLSQLNGEP--VEPYMYI 254
            :::.|.||:.|...:|..:..: .||||:.:.:  .:.||.:   |.|.....|..  .:.::::
Worm   209 MQNVLCPRSGGLQLALDNLSTL-DAIYDVTVMYGQMRMAERRGLAPGMFDFCCGSQQFKQLHIHL 272

  Fly   255 RRVPLDVVPDDEKEAAAWMQDFFAEKDKIIDSFH----ETGS 292
            .|:|:|.||..:.|...|..:.|.:|::|||.|:    .|||
Worm   273 DRIPIDEVPKAKLELRTWTIERFTKKERIIDEFYSEKPSTGS 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Agpat4	NP_001261942.1	PLN02380	12..366	CDD:178006	79/301 (26%)
		LPLAT_LCLAT1-like	58..255	CDD:153252	54/212 (25%)
		Acyltransf_C	243..320	CDD:292694	17/56 (30%)
acl-11	NP_491479.2	LPLAT_LCLAT1-like	63..273	CDD:153252	54/212 (25%)
acl-11	NP_491479.2	Acyltransf_C	266..>309	CDD:374349	13/42 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG51956
OrthoDB	1	1.010	-	-		D959325at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3473
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.860