DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Agpat4 and Agpat4

DIOPT Version :9

Sequence 1:	NP_001261942.1	Gene:	Agpat4 / 39819	FlyBaseID:	FBgn0036622	Length:	380	Species:	Drosophila melanogaster
Sequence 2:	XP_006227918.1	Gene:	Agpat4 / 170919	RGDID:	619916	Length:	414	Species:	Rattus norvegicus

Alignment Length:	373	Identity:	132/373 - (35%)
Similarity:	217/373 - (58%)	Gaps:	21/373 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LGRLLIAVTFFTCGFFVNIGQLLLILLVRPFDKKLSRSLAYYLHYSFYCILVCVAEWYAGSKLRV 71
            |..|:....|...|..||..| |..|::.|.:|:|.|.:...|.|.....||.:.||::|::..:
  Rat    48 LCHLVFCYVFIASGLIVNAIQ-LCTLVIWPINKQLFRKINARLCYCVSSQLVMLLEWWSGTECTI 111

  Fly    72 YIDPQDEQKFFGKEHGLLLMNHTYEIDWLTAWMITDKLGNLGGTKAYAKKMLRYVPVLGWVWWMA 136
            |.||: ....:|||:.::::||.:|||:|..|.:.::||.||.:|..|||.|.|||::||:|:..
  Rat   112 YTDPK-ASPHYGKENAIVVLNHKFEIDFLCGWSLAERLGILGNSKVLAKKELAYVPIIGWMWYFV 175

  Fly   137 EFIFLDRNFEKDKVVIKTQLKEVFSYPDPVWLLLNAEGTRFTPAKHELSVKFAEERGLPLLKHHL 201
            |.||..|.:|:|:..:...|..:..||:....|::.||||||..||::|::.|:.:|||.|||||
  Rat   176 EMIFCTRKWEQDRQTVAKSLLHLRDYPEKYLFLIHCEGTRFTEKKHQISMQVAQAKGLPSLKHHL 240

  Fly   202 IPRTKGFTTSLPTMRGICPAIYDINLAFKKNAEPKPTMLSQLNGEPVEPYMYIRRVPLDVVPDDE 266
            :||||||..::..:|.:.||:||..|.|:.|  ..||:|..|||:......|:||:|::.:|:||
  Rat   241 LPRTKGFAITVKCLRDVVPAVYDCTLNFRNN--ENPTLLGVLNGKKYHADCYVRRIPMEDIPEDE 303

  Fly   267 KEAAAWMQDFFAEKDKIIDSFHETGSFFKNSGVKEVPEKIYKP--RLSTLLNFLGWATFAVLCIL 329
            .:.:||:...:.|||...:.::.||.|         ||..:.|  |..:|:|:|.||:..:....
  Rat   304 DKCSAWLHKLYQEKDAFQEEYYRTGVF---------PETPWVPPRRPWSLVNWLFWASLLLYPFF 359

  Fly   330 HYLVTSLVAGNWFGFITVLSILGGFYSL---MEYAVNASKISKASAYG 374
            .:||:.:.:|:   .:|:.|::..|...   :.:.:..::|.|.||||
  Rat   360 QFLVSMVSSGS---SVTLASLVLIFCMASMGVRWMIGVTEIDKGSAYG 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Agpat4	NP_001261942.1	PLN02380	12..366	CDD:178006	124/358 (35%)
		LPLAT_LCLAT1-like	58..255	CDD:153252	81/196 (41%)
		Acyltransf_C	243..320	CDD:292694	25/78 (32%)
Agpat4	XP_006227918.1	PlsC	51..325	CDD:223282	107/273 (39%)
		LPLAT_LCLAT1-like	98..292	CDD:153252	81/193 (42%)
		Acyltransf_C	279..350	CDD:292694	22/70 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351807
Domainoid	1	1.000	129	1.000	Domainoid score	I5116
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	295	1.000	Inparanoid score	I2662
OMA	1	1.010	-	-		QHG51956
OrthoDB	1	1.010	-	-		D482283at33208
OrthoFinder	1	1.000	-	-		FOG0001449
OrthoInspector	1	1.000	-	-		mtm9064
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10983
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1337
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.870