DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Agpat4 and lclat1

DIOPT Version :9

Sequence 1:	NP_001261942.1	Gene:	Agpat4 / 39819	FlyBaseID:	FBgn0036622	Length:	380	Species:	Drosophila melanogaster
Sequence 2:	NP_001135517.1	Gene:	lclat1 / 100216057	XenbaseID:	XB-GENE-5993059	Length:	371	Species:	Xenopus tropicalis

Alignment Length:	365	Identity:	101/365 - (27%)
Similarity:	166/365 - (45%)	Gaps:	33/365 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 VTFFTCGFFVNI---GQLLLILLVRP--FDKKLSRSLAYYLHYSFYCILVCVAEWYAGSKLRVYI 73
            :..|...||.:|   |..|.::||.|  :.....|.:|.:|     .:.|.:.|...|:|:.:..
Frog    11 LALFLGSFFGSIFMLGPFLPLMLVSPSWYRWITDRIVATWL-----TLPVALLELVFGAKVVITG 70

  Fly    74 DPQDEQKFFGKEHGLLLMNHTYEIDWLTAWMITDKLGNLGGTKAYAKKMLRYVPVLGWVWWMAEF 138
            |     .|...|..:::|||...:||:..|....:...|...|...|..|:.||..||...:|.|
Frog    71 D-----GFIPGERSVIIMNHRTRLDWMFLWNCLLRYSYLRLEKICLKSSLKAVPGFGWAMQVAAF 130

  Fly   139 IFLDRNFEKDKVVIKTQLKEVFSYPDPVWLLLNAEGTRFTPAKHELSVKFAEERGLPLLKHHLIP 203
            ||:.|.:|.||...:..|.......:.:.||:..|||..|......|.:|||:..|...::.|.|
Frog   131 IFIHRKWEDDKNHFEAMLDYFCDIKEHLQLLIFPEGTDLTDNTKARSDEFAEKNKLQKYEYVLHP 195

  Fly   204 RTKGFTTSLPTMR--GICPAIYDINLAFKKNAEPKPTMLSQLNGE-PVEPYMYIRRVPLDVVPDD 265
            ||.|||..:..:|  ....||:||.:|:..|. |: |....|||. |.|.:.::.|.|:..:|..
Frog   196 RTTGFTFIVDRLREGNNLDAIHDITVAYPHNI-PQ-TEKHILNGNFPKEIHFHVCRYPVSSLPVS 258

  Fly   266 EKEAAAWMQDFFAEKDKIIDSFHETGSFFKNSGVKEVP--EKIYKPRLSTLLNFLGWATFAV-LC 327
            ::|...|.|..:.||:..:.:|::...:|..:....:|  :...:..|..:.:.|.|..|.: :.
Frog   259 KEELQLWCQQRWKEKEDRLRAFYQGERYFDATRRSRIPPCKSELRVHLIKMASLLYWTLFPLAMI 323

  Fly   328 ILHYLVTSLVAGNWFGFITVL------SILGGFYSLMEYA 361
            :|.||.:.:   .|:..:||:      .|.||. .|:|.|
Frog   324 VLLYLYSPV---RWYFLVTVVIFVLQEKIFGGL-ELIELA 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Agpat4	NP_001261942.1	PLN02380	12..366	CDD:178006	101/365 (28%)
		LPLAT_LCLAT1-like	58..255	CDD:153252	62/199 (31%)
		Acyltransf_C	243..320	CDD:292694	18/79 (23%)
lclat1	NP_001135517.1	LPLAT_LCLAT1-like	55..247	CDD:153252	62/198 (31%)
lclat1	NP_001135517.1	Acyltransf_C	233..302	CDD:374349	16/68 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D959325at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3473
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.040