Protein Alignment roq and RNF227

DIOPT Version :9

• Sequence 1: NP_001261940.1
• Gene: roq / 39818
• FlyBaseID: FBgn0036621
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: NP_001345628.1
• Gene: RNF227 / 284023
• HGNCID: 27571
• Length: 190
• Species: Homo sapiens
• Alignment Length: 222
• Identity: 51/222 - (22%)
• Similarity: 65/222 - (29%)
• Gaps: 92/222 - (41%)

  Fly     3 IQAPSWTD--FLNCPICCNEFAASQRCPVSL------GCGHTICKLCLTTLYNR----------- 48
            ::.||..:  .|:|.||...|....|.|..|      .||||||..||..|..|
Human     5 VRVPSLPERGELDCNICYRPFNLGCRAPRRLPGTARARCGHTICTACLRELAARGDGGGAAARVV 69

  Fly    49 ------QCPFDQTVIVSDIDNLPINHALLQLVKDSEL---LELAPPPPSVQKLEPEHLKCYQLGQ 104
                  .|||.:..     ..|| ...|.::..||:|   ||           |....||.:
Human    70 RLRRVVTCPFCRAP-----SQLP-RGGLTEMALDSDLWSRLE-----------EKARAKCER--- 114

  Fly   105 RCIEELALHLKSFLNLNGNGNLLTRPMLRKLVTLVNCQLMEEEGRVRALRAARSLGERTVTELIL 169
               :|.....|...:.:|..                    ||||........||.|
Human   115 ---DEAGNPAKESSDADGEA--------------------EEEGESEKGAGPRSAG--------- 147

  Fly   170 QHQNPQQLSSNLWAAVRTRGCQFLGPA 196
                        |.|:|....:.||||
Human   148 ------------WRALRRLWDRVLGPA 162

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
roq	NP_001261940.1	zf-RING_5	13..55	CDD:291308	20/64 (31%)
		zf-CCCH	418..444	CDD:279036
RNF227	NP_001345628.1	RING_Ubox	17..>55	CDD:327409	15/37 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	111..145		9/59 (15%)
		DUF4632	117..187	CDD:317804	16/87 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156527
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930