DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment roq and rcs-1

DIOPT Version :9

Sequence 1:	NP_001261940.1	Gene:	roq / 39818	FlyBaseID:	FBgn0036621	Length:	819	Species:	Drosophila melanogaster
Sequence 2:	NP_001123114.1	Gene:	rcs-1 / 259719	WormBaseID:	WBGene00016190	Length:	302	Species:	Caenorhabditis elegans

Alignment Length:	327	Identity:	69/327 - (21%)
Similarity:	131/327 - (40%)	Gaps:	83/327 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 FLNCPICCNEFA--ASQRCPVSLGCGHTICKLCLTTLYNR---QCPFDQTV---IVSDIDNLPIN 67
            |..|.||.:.|:  .|:..|.:|.|||.:|..|:|.:.|.   :|||.:||   :.:||..|..|
Worm     3 FPKCKICFDRFSDTDSEHIPRNLTCGHALCHKCITAMVNNSTVECPFCRTVTNIVNNDITKLLKN 67

  Fly    68 HALLQLVKDS-------ELLELAPPPPSVQKLEPEHLK---CYQLGQRCIEELALHLKS---FLN 119
            .||:::::|:       :::.:....|.:.|..|.:|.   |...|  |..:..|..::   |.|
Worm    68 FALIEVIEDARYSLNKKDVVVVNSNSPPMCKNHPHNLAEFVCVTSG--CKSQCKLMCRTCEEFGN 130

  Fly   120 LNGNGNLLTRPMLRKLVTLVNCQLMEEEGRVRALRAARSLGERTVTELILQHQNPQQLSSNLWAA 184
            ..|:...|.:....|:.|::|....:.|....::::.           |.|::|.|:       :
Worm   131 HKGHTRGLLQEEAAKMRTVLNNSETKLENFCDSIQSC-----------IEQYKNAQR-------S 177

  Fly   185 VRTRGCQFLGPAMQEEVLKLVLLALEEGSALSRKVLVMFVVQRLEPKFPQASKTSIGHVVQLLYR 249
            ..:.|..:          |..:.::||.            .::::....|..|.::   |:|...
Worm   178 FESSGATY----------KAKVKSIEEH------------FKKIKEMVAQREKETL---VELKDA 217

  Fly   250 ASC-----------FKVSKREADSSLMQLKEEFRTYDALRREHDAQIVQ------IATEAGLRIA 297
            |.|           ..|..:.....|..:||......|.....::||::      |||::.:..|
Worm   218 ADCCLDDNKKKMEILSVGHQRFKQKLTDMKEFHNINQAGLLSKESQIMELVEMAKIATQSNVVNA 282

  Fly   298 PE 299
            |:
Worm   283 PQ 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
roq	NP_001261940.1	zf-RING_5	13..55	CDD:291308	17/46 (37%)
roq	NP_001261940.1	zf-CCCH	418..444	CDD:279036
rcs-1	NP_001123114.1	RING-HC_malin	5..51	CDD:319430	17/45 (38%)
rcs-1	NP_001123114.1	Bbox_SF	94..143	CDD:381767	12/50 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910