| Sequence 1: | NP_001261940.1 | Gene: | roq / 39818 | FlyBaseID: | FBgn0036621 | Length: | 819 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001287779.1 | Gene: | RC3H1 / 149041 | HGNCID: | 29434 | Length: | 1134 | Species: | Homo sapiens |
| Alignment Length: | 699 | Identity: | 362/699 - (51%) |
|---|---|---|---|
| Similarity: | 437/699 - (62%) | Gaps: | 104/699 - (14%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1 MPIQAPSWTDFLNCPICCNEFAASQRCPVSLGCGHTICKLCLTTLYNRQCPFDQTVIVSDIDNLP 65
Fly 66 INHALLQLVKDSELLELAPPPPSVQKLEP-------EHLKCYQLGQRCIEELALHLKSFLNLNGN 123
Fly 124 G------NLLTRPMLRKLVTLVNCQLMEEEGRVRALRAARSLGERTVTELILQHQNPQQLSSNLW 182
Fly 183 AAVRTRGCQFLGPAMQEEVLKLVLLALEEGSALSRKVLVMFVVQRLEPKFPQASKTSIGHVVQLL 247
Fly 248 YRASCFKVSKREADSSLMQLKEEFRTYDALRREHDAQIVQIATEAGLRIAPEQWSSLLYGDVMHK 312
Fly 313 SHMQSIIDKLQTPSSFAQSVQELVIALQRTSDPAKLSSLHHHLKYLANIDPCAEVAP--WSVLAE 375
Fly 376 ALDAVRHSVVGLVNFLQHHGVRKAQDGISGGGSGGTTNSNP----KYKISLCRDLNVRRVCPRGS 436
Fly 437 SCTFAHSQEEVERYRARNRGKHMKTPLALQ-------GPPAVGV----GAIKKPLGEQEGPPLGN 490
Fly 491 MPPMLPMSPMHYMGSPRGYLDPSLGLSPGGGLPPSHHSPITRLIVPSRYDSRFSGFGGGTPRI-- 553
Fly 554 PSPREYQANPV----APTQRNANPPNFSVNSNLH---KGYML-PASGGDVFH-----LANPWEQA 605
Fly 606 YLAQQQH---PPQHPQQ-QQPPSSKPNPSRPLSILPATADTSFFEKKPP 650 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| roq | NP_001261940.1 | zf-RING_5 | 13..55 | CDD:291308 | 23/41 (56%) |
| zf-CCCH | 418..444 | CDD:279036 | 16/25 (64%) | ||
| RC3H1 | NP_001287779.1 | RING | 14..52 | CDD:214546 | 20/37 (54%) |
| HEPN-N. /evidence=ECO:0000269|PubMed:26489670 | 89..173 | 50/83 (60%) | |||
| ROQ. /evidence=ECO:0000269|PubMed:25504471, ECO:0000269|PubMed:26489670 | 174..326 | 137/151 (91%) | |||
| HEPN-C. /evidence=ECO:0000269|PubMed:26489670 | 327..396 | 40/68 (59%) | |||
| zf-CCCH | 414..440 | CDD:279036 | 16/25 (64%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 505..543 | 11/48 (23%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1000..1019 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1058..1078 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1095..1134 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165156525 | |
| Domainoid | 1 | 1.000 | 304 | 1.000 | Domainoid score | I1381 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG3161 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 604 | 1.000 | Inparanoid score | I946 |
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S5168 |
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0004107 | |
| OrthoInspector | 1 | 1.000 | - | - | otm40880 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_105901 | |
| Panther | 1 | 1.100 | - | - | O | PTHR13139 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R3350 |
| SonicParanoid | 1 | 1.000 | - | - | X2848 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 14 | 13.730 | |||||