DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4842 and CG18814

DIOPT Version :9

Sequence 1:	NP_648885.1	Gene:	CG4842 / 39817	FlyBaseID:	FBgn0036620	Length:	259	Species:	Drosophila melanogaster
Sequence 2:	NP_652673.2	Gene:	CG18814 / 59175	FlyBaseID:	FBgn0042137	Length:	267	Species:	Drosophila melanogaster

Alignment Length:	260	Identity:	195/260 - (75%)
Similarity:	231/260 - (88%)	Gaps:	1/260 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDLAGKNVVYLGGFGGIGQKCVQELLQRPIKALAIFDLNANEQLLAKWKSQHPDTDVFYHKLDIT 65
            |||.||||||||||||||:|||||||::.||.||||||..::.|||:||.|||||::||.|:|||
  Fly     1 MDLEGKNVVYLGGFGGIGKKCVQELLKKQIKGLAIFDLIVDDDLLAEWKKQHPDTEIFYQKMDIT 65

  Fly    66 QKSDIDAAYKATAERFGHFDVVVNGSGLMNDRLVELTIQINLLGVINSTLTALEYMDKAKGGKGG 130
            ||||||||||||||:.||||||||||||::||.:||||||||:|||||||||||||||:|||:||
  Fly    66 QKSDIDAAYKATAEKLGHFDVVVNGSGLLDDRRIELTIQINLVGVINSTLTALEYMDKSKGGRGG 130

  Fly   131 LIVNISSVAGLQPTAIMAIYSAAKTGVTTFTRAMANPYFYAHSGVGFLTICPGFTDTGLLEDIGN 195
            ||||||||||||||.:|||||.:||||||||||||:|..||||||||:|||||:|:||:|:||..
  Fly   131 LIVNISSVAGLQPTPLMAIYSTSKTGVTTFTRAMASPIHYAHSGVGFITICPGYTNTGILKDIDK 195

  Fly   196 KTTFT-YDTPMLAMFNRVKRQKAEDCARNLVSAIETSKNGTVLMLEMGETTEVDMPVMWKPQLDN 259
            ||||. |:|.|..:|::||.|.||.||||:|:||||:|||.|||||:||..|:|:|.:|.||||:
  Fly   196 KTTFPFYETRMRTVFSKVKGQTAEVCARNIVNAIETAKNGAVLMLELGEIHELDIPNLWNPQLDD 260

Fly 260 259
Fly 261 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4842	NP_648885.1	NADB_Rossmann	6..247	CDD:304358	183/241 (76%)
CG4842	NP_648885.1	adh_short	6..194	CDD:278532	150/187 (80%)
CG18814	NP_652673.2	NADB_Rossmann	6..248	CDD:304358	183/241 (76%)
CG18814	NP_652673.2	adh_short	6..196	CDD:278532	151/189 (80%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455189
Domainoid	1	1.000	96	1.000	Domainoid score	I2453
eggNOG	1	0.900	-	-		E2759_KOG4169
Homologene	1	1.000	-	-		H134459
Inparanoid	1	1.050	136	1.000	Inparanoid score	I4534
Isobase	1	0.950	-	0.861353	Normalized mean entropy	S2756
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1053465at2759
OrthoFinder	1	1.000	-	-		FOG0008550
OrthoInspector	1	1.000	-	-		mtm6395
orthoMCL	1	0.900	-	-		OOG6_100916
Panther	1	1.100	-	-	P	PTHR44229
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2961
	13	12.750