Protein Alignment CG4842 and HPGD

DIOPT Version :9

• Sequence 1: NP_648885.1
• Gene: CG4842 / 39817
• FlyBaseID: FBgn0036620
• Length: 259
• Species: Drosophila melanogaster
• Sequence 2: NP_000851.2
• Gene: HPGD / 3248
• HGNCID: 5154
• Length: 266
• Species: Homo sapiens
• Alignment Length: 251
• Identity: 82/251 - (32%)
• Similarity: 124/251 - (49%)
• Gaps: 21/251 - (8%)

  Fly     1 MDLAGKNVVYLGGFGGIGQKCVQELLQRPIK-ALAIFDLNANEQLLAKWKSQHPDTDVFYHKLDI 64
            |.:.||..:..|...|||:...:.||.:..| ||..::|.|..|..|....|.......:.:.|:
Human     1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDV 65

  Fly    65 TQKSDIDAAYKATAERFGHFDVVVNGSGLMNDRLVELTIQINLLGVINSTLTALEYMDKAKGGKG 129
            ..:..:...::...:.||..|::||.:|:.|::..|.|:||||:.||:.|...|:||.|..||:|
Human    66 ADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDYMSKQNGGEG 130

  Fly   130 GLIVNISSVAGLQPTAIMAIYSAAKTGVTTFTRAMANPYFYAHSGVGFLTICPGFTDTGLLEDIG 194
            |:|:|:||:|||.|.|...:|.|:|.|:..|||:.|......:|||....|||||.:|.:||.|.
Human   131 GIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAILESIE 195

  Fly   195 N--------------KTTFTY----DTPMLAMFNRVKRQKAEDCARNLVSAIETSK 232
            .              |....|    |.|::|  |.:.....:|.....:..|.|||
Human   196 KEENMGQYIEYKDHIKDMIKYYGILDPPLIA--NGLITLIEDDALNGAIMKITTSK 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4842	NP_648885.1	NADB_Rossmann	6..247	CDD:304358	80/246 (33%)
		adh_short	6..194	CDD:278532	68/188 (36%)
HPGD	NP_000851.2	ADH_SDR_c_like	6..254	CDD:187584	80/246 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151368
Domainoid	1	1.000	138	1.000	Domainoid score	I4841
eggNOG	1	0.900	-	-		E2759_KOG4169
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	144	1.000	Inparanoid score	I4450
Isobase	1	0.950	-	0.861353	Normalized mean entropy	S2756
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1053465at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm40699
orthoMCL	1	0.900	-	-		OOG6_100916
Panther	1	1.100	-	-	O	PTHR44229
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	12	11.710