Protein Alignment CG4842 and HSD17B10

DIOPT Version :10

• Sequence 1: NP_648885.1
• Gene: CG4842 / 39817
• FlyBaseID: FBgn0036620
• Length: 259
• Species: Drosophila melanogaster
• Sequence 2: NP_004484.1
• Gene: HSD17B10 / 3028
• HGNCID: 4800
• Length: 261
• Species: Homo sapiens
• Alignment Length: 212
• Identity: 56/212 - (26%)
• Similarity: 90/212 - (42%)
• Gaps: 29/212 - (13%)

  Fly     5 GKNVVYLGGFGGIGQKCVQELLQRPIKALAIFDL-NANEQLLAKWKSQHPDTDVFYHKLDITQKS 68
            |...|..||..|:|....:.|:.:...|: :.|| |:..:..||    ....:..:...|:|.:.
Human    10 GLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEAQAK----KLGNNCVFAPADVTSEK 69

  Fly    69 DIDAAYKATAERFGHFDVVVNGSGL----------------MNDRLVELTIQINLLGVINSTLTA 117
            |:..|......:||..||.||.:|:                :.|  .:..:.:||:|..|.....
Human    70 DVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLED--FQRVLDVNLMGTFNVIRLV 132

  Fly   118 LEYM---DKAKGGKGGLIVNISSVAGLQPTAIMAIYSAAKTGVTTFTRAMANPYFYAHSGVGFLT 179
            ...|   :..:||:.|:|:|.:|||..:.....|.|||:|.|:...|..:|..  .|..|:..:|
Human   133 AGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD--LAPIGIRVMT 195

  Fly   180 ICPGFTDTGLLEDIGNK 196
            |.||...|.||..:..|
Human   196 IAPGLFGTPLLTSLPEK 212

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4842	NP_648885.1	Rossmann-fold NAD(P)(+)-binding proteins	6..247	CDD:473865	55/211 (26%)
HSD17B10	NP_004484.1	HSD10-like_SDR_c	9..261	CDD:187629	56/212 (26%)