Protein Alignment CG4842 and Hpgd

DIOPT Version :10

• Sequence 1: NP_648885.1
• Gene: CG4842 / 39817
• FlyBaseID: FBgn0036620
• Length: 259
• Species: Drosophila melanogaster
• Sequence 2: NP_032304.2
• Gene: Hpgd / 15446
• MGIID: 108085
• Length: 269
• Species: Mus musculus
• Alignment Length: 245
• Identity: 80/245 - (32%)
• Similarity: 123/245 - (50%)
• Gaps: 6/245 - (2%)

  Fly     1 MDLAGKNVVYLGGFGGIGQKCVQELLQRPIK-ALAIFDLNANEQLLAKWKSQHPDTDVFYHKLDI 64
            |.:.||..:..|...|||:...:.||....| ||..::|.|..:..|....|.......:.:.|:
Mouse     1 MHVNGKVALVTGAAQGIGKAFAEALLLHGAKVALVDWNLEAGVKCKAALDEQFEPQKTLFVQCDV 65

  Fly    65 TQKSDIDAAYKATAERFGHFDVVVNGSGLMNDRLVELTIQINLLGVINSTLTALEYMDKAKGGKG 129
            ..:..:...::...:.||..|::||.:|:.|::..|.|:||||:.||:.|...|:||.|..||:|
Mouse    66 ADQKQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEQTLQINLVSVISGTYLGLDYMSKQNGGEG 130

  Fly   130 GLIVNISSVAGLQPTAIMAIYSAAKTGVTTFTRAMANPYFYAHSGVGFLTICPGFTDTGLLEDIG 194
            |:|:|:||:|||.|.|...:|.|:|.|:..|||:.|.......|||....|||||.||.:||.|.
Mouse   131 GIIINMSSLAGLMPVAQQPVYCASKHGIIGFTRSAAMAANLMKSGVRLNVICPGFVDTPILESIE 195

  Fly   195 NKTT----FTYDTPMLAMFNRVKRQKAEDCARNLVSAIE-TSKNGTVLML 239
            .:..    ..|...:.||............|..|::.|| .:.||.::.:
Mouse   196 KEENMGQYIEYKDQIKAMMKFYGVLHPSTIANGLINLIEDDALNGAIMKI 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4842	NP_648885.1	Rossmann-fold NAD(P)(+)-binding proteins	6..247	CDD:473865	78/240 (33%)
Hpgd	NP_032304.2	ADH_SDR_c_like	6..254	CDD:187584	78/240 (33%)