DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ringer and tppp3

DIOPT Version :9

Sequence 1:	NP_001246792.1	Gene:	ringer / 39813	FlyBaseID:	FBgn0266417	Length:	192	Species:	Drosophila melanogaster
Sequence 2:	NP_958492.2	Gene:	tppp3 / 393825	ZFINID:	ZDB-GENE-040426-1909	Length:	177	Species:	Danio rerio

Alignment Length:	178	Identity:	73/178 - (41%)
Similarity:	97/178 - (54%)	Gaps:	19/178 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 ATELAQLALEDEPKVSFSDQFKAFSKFGDSKSDGKLITLSQSDKWMKQAKVID-KKITTTDTGIH 84
            :|::.||.          :.||.|:..||:|:.||.:......|..|..|||| |.:|:||..|.
Zfish     4 STDMDQLL----------NSFKKFAVHGDTKATGKELNGKNWAKLCKDCKVIDGKNVTSTDVDIV 58

  Fly    85 FKKFKAMK---ISLSDYNKFLDDLAKTK-----KVELSEIKQKLASCGAPGVVSVSAGKAAAAVD 141
            |.|.||..   |:..::.|.|::||..:     |.|..|...||.....|..:.|:.....||||
Zfish    59 FTKVKAKTSRVITYEEFQKALEELAPKRFKGQSKEEALESIYKLIEGKEPTNIGVTKVAKTAAVD 123

  Fly   142 RLTDTSKYTGSHKERFDASGKGKGIAGRRNVVDGSGYVSGYQHKDTYD 189
            |||||||||||||||||.:|||||..||..:|:.:|||..|::...||
Zfish   124 RLTDTSKYTGSHKERFDETGKGKGKGGREEIVEHTGYVGAYKNAGKYD 171

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ringer	NP_001246792.1	p25-alpha	39..184	CDD:368481	68/153 (44%)
tppp3	NP_958492.2	p25-alpha	13..171	CDD:283231	68/157 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577630
Domainoid	1	1.000	111	1.000	Domainoid score	I6182
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	115	1.000	Inparanoid score	I4805
OMA	1	1.010	-	-		QHG52260
OrthoDB	1	1.010	-	-		D1317210at2759
OrthoFinder	1	1.000	-	-		FOG0002323
OrthoInspector	1	1.000	-	-		otm26422
orthoMCL	1	0.900	-	-		OOG6_102553
Panther	1	1.100	-	-	O	PTHR12932
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2904
SonicParanoid	1	1.000	-	-		X1531
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.940