Protein Alignment Pdh and YDL114W

DIOPT Version :10

• Sequence 1: NP_524105.2
• Gene: Pdh / 39812
• FlyBaseID: FBgn0011693
• Length: 278
• Species: Drosophila melanogaster
• Sequence 2: NP_010169.1
• Gene: YDL114W / 851444
• SGDID: S000002272
• Length: 308
• Species: Saccharomyces cerevisiae
• Alignment Length: 229
• Identity: 61/229 - (26%)
• Similarity: 119/229 - (51%)
• Gaps: 50/229 - (21%)

  Fly    19 SFRGKN--AVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPT------QSVM 75
            |...||  |::|||:.|:|.:::|: |:....||.:.|:|           :.||      .::.
Yeast    33 SILSKNATALITGGSSGLGFELAKE-LSRRINKVIVADIQ-----------SFPTFAQVEYNNIF 85

  Fly    76 IIKMDVANKKGVEATYEEIAKTFGNIDIVVNVAGI--------FNDKDVQRTLLVNLGG---IIN 129
            ..:.|:.:...::...:.|.:..|||:|::|.||:        ..:|:|::.:.:||.|   ||:
Yeast    86 YYQCDITSLDEIKNLKKAIERDHGNINIIINNAGVAHIKKLEHMTNKEVEQLIDINLIGAYRIIS 150

  Fly   130 STLSALPYMGKDNGGKGGIVVNMSSVVG-LDPMFIIPVYGATKAGIINFTRCLANEKYYQ----- 188
            :....:    .||  :.|.::|::||:| |.|..:.. |||:|..:|.|.:|::  ::::
Yeast   151 TFAEDM----IDN--REGFIINIASVLGELTPARLTS-YGASKGAMIGFHKCMS--RHFRSLSTE 206

  Fly   189 --RSGIKFVTVCPGATMTDMFTNF--TEKIIFPE 218
              ::|||.:.||||...|:||.:.  ..|::.|:
Yeast   207 CNKTGIKTLLVCPGKIKTNMFIDVPTPSKLLAPD 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdh	NP_524105.2	Rossmann-fold NAD(P)(+)-binding proteins	23..259	CDD:473865	60/225 (27%)
YDL114W	NP_010169.1	17beta-HSDXI-like_SDR_c	40..282	CDD:187598	58/222 (26%)