Protein Alignment Pdh and hsd17b10

DIOPT Version :10

• Sequence 1: NP_524105.2
• Gene: Pdh / 39812
• FlyBaseID: FBgn0011693
• Length: 278
• Species: Drosophila melanogaster
• Sequence 2: NP_001006098.1
• Gene: hsd17b10 / 450078
• ZFINID: ZDB-GENE-041010-201
• Length: 260
• Species: Danio rerio
• Alignment Length: 280
• Identity: 79/280 - (28%)
• Similarity: 120/280 - (42%)
• Gaps: 59/280 - (21%)

  Fly    19 SFRGKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAA-------HPTQSVMI 76
            |.:|...:|||||.|:|....::|:..||:.| |:||..:  :..|:.||       .||
Zfish     6 SVKGMVGLVTGGASGLGRATVERLIKHGASAV-ILDLPSS--DGHKVAAALGDRCAFAPT----- 62

  Fly    77 IKMDVANKKGVEATYEEIAKTFGNIDIVVNVAGI------FNDK--------DVQRTLLVNLGGI 127
               ||.::..|.:..:...:.:|.:|:.||.|||      :|.|        |..|.:.||:.|.
Zfish    63 ---DVTSESDVRSALDLAKEKYGKVDLAVNCAGIAVAVKTYNFKKDLPHSLEDFTRVITVNIAGT 124

  Fly   128 INSTLSALPYMGK---DNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCLANEKYYQR 189
            .|....|:..|||   |..|..|.:||.:||...|.......|.|:|.||:..|..:|.:  ...
Zfish   125 FNVIRLAVGEMGKNEPDADGHRGCIVNTASVAAYDGQVGQAAYSASKGGIVGMTLPIARD--LAP 187

  Fly   190 SGIKFVTVCPGATMTDMFTNFTEK--------IIFPETSDETYRILDRLNKQSAADVSRCILNVL 246
            .||:.||:.||...|.:.....||        :.||          .||.  ..|:.:..:.::.
Zfish   188 MGIRVVTIAPGLFATPLLAGLPEKVQSFLARQVPFP----------SRLG--DPAEFAHLVTSIA 240

  Fly   247 EKDK-NGAVYVIEGK-RVYP 264
            |... ||.|..::|. |:.|
Zfish   241 ENPMINGEVIRLDGAIRMQP 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdh	NP_524105.2	Rossmann-fold NAD(P)(+)-binding proteins	23..259	CDD:473865	74/268 (28%)
hsd17b10	NP_001006098.1	HSD10-like_SDR_c	8..260	CDD:187629	77/276 (28%)