Protein Alignment Pdh and Hpgd

DIOPT Version :9

• Sequence 1: NP_524105.2
• Gene: Pdh / 39812
• FlyBaseID: FBgn0011693
• Length: 278
• Species: Drosophila melanogaster
• Sequence 2: NP_032304.2
• Gene: Hpgd / 15446
• MGIID: 108085
• Length: 269
• Species: Mus musculus
• Alignment Length: 271
• Identity: 96/271 - (35%)
• Similarity: 150/271 - (55%)
• Gaps: 19/271 - (7%)

  Fly    18 MSFRGKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAA----HPTQSVMIIK 78
            |...||.|:|||.|.|||...::.||..| ||||::|.  |||..||.:||    ...|..:.::
Mouse     1 MHVNGKVALVTGAAQGIGKAFAEALLLHG-AKVALVDW--NLEAGVKCKAALDEQFEPQKTLFVQ 62

  Fly    79 MDVANKKGVEATYEEIAKTFGNIDIVVNVAGIFNDKDVQRTLLVNLGGIINSTLSALPYMGKDNG 143
            .|||::|.:..|:.::...||.:||:||.||:.|:|:.::||.:||..:|:.|...|.||.|.||
Mouse    63 CDVADQKQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEQTLQINLVSVISGTYLGLDYMSKQNG 127

  Fly   144 GKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCLANEKYYQRSGIKFVTVCPGATMTDMFT 208
            |:|||::||||:.||.|:...|||.|:|.|||.|||..|......:||::...:|||...|.:..
Mouse   128 GEGGIIINMSSLAGLMPVAQQPVYCASKHGIIGFTRSAAMAANLMKSGVRLNVICPGFVDTPILE 192

  Fly   209 NFTEKI---IFPETSDETYRILDRLNKQSAADVSRCILNVLEKDK-NGAVYVIEGKR-------- 261
            :..::.   .:.|..|:...::........:.::..::|::|.|. |||:..|...:
Mouse   193 SIEKEENMGQYIEYKDQIKAMMKFYGVLHPSTIANGLINLIEDDALNGAIMKITASKGIHFQDYD 257

  Fly   262 VYPLEIKPQWT 272
            :.||.:|...|
Mouse   258 ISPLLVKAPLT 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdh	NP_524105.2	NADB_Rossmann	23..259	CDD:304358	90/243 (37%)
		adh_short	23..214	CDD:278532	81/194 (42%)
Hpgd	NP_032304.2	ADH_SDR_c_like	6..254	CDD:187584	90/250 (36%)
		adh_short	6..199	CDD:278532	81/195 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841505
Domainoid	1	1.000	142	1.000	Domainoid score	I4666
eggNOG	1	0.900	-	-		E2759_KOG4169
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	149	1.000	Inparanoid score	I4369
Isobase	1	0.950	-	0.861353	Normalized mean entropy	S2756
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1053465at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm42773
orthoMCL	1	0.900	-	-		OOG6_100916
Panther	1	1.100	-	-	O	PTHR44229
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R7321
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.740