DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4998 and CG14760

DIOPT Version :9

Sequence 1:	NP_001036609.1	Gene:	CG4998 / 39808	FlyBaseID:	FBgn0036612	Length:	1185	Species:	Drosophila melanogaster
Sequence 2:	NP_610366.1	Gene:	CG14760 / 35802	FlyBaseID:	FBgn0033277	Length:	529	Species:	Drosophila melanogaster

Alignment Length:	514	Identity:	109/514 - (21%)
Similarity:	196/514 - (38%)	Gaps:	121/514 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   747 YPHFYGGTGPGLHFSVEMVPSTPIFEYHSGPSVQ------------YHHHHESSPYESSFNSIYP 799
            ||..| ..|....::|| .|...:.::.....::            :|.:.|.....:
  Fly    42 YPALY-PVGTSCRYAVE-APKDHVLQFKCELQLRTLSTDLKCRTEVFHFNSEGDEVLT------- 97

  Fly   800 GSSPDFGGYGEYSQ--HVERS--ANVSGGDTDRPSNSGRRGKQLNLGPLYNIPTPAPGEAAGSDR 860
             ||..|.|.|::.:  .:.|:  :.:|.|.::.||....:.| |:..|..:..|.||...:..::
  Fly    98 -SSEYFCGSGKFERKSFLNRAVISYISSGHSEPPSAVKLKDK-LHAVPTTSTTTEAPQAVSIEEQ 160

  Fly   861 ITFPRDRRRRSVED----------------GVWAGAA--------PKEQR-----AYYGNRPVEK 896
            ............|:                ||....|        .:|.|     .|....|:..
  Fly   161 DAEEEQEEEEEPEEADEDLSDEVLHVLQDVGVSDALAYVASLLYDVEESRKSSTTIYLDKLPIRS 225

  Fly   897 TCRIN----EVCCRRPLRPQAPPQQFGR-------------CGVRNAAGITGRIKNPVYVDGDSE 944
            :.:.:    .:....|....:|....||             ||.....    ||.:|  .:.::.
  Fly   226 SSKTSAKRARIVSSYPTAAPSPGHGGGRFSCLVEAFQPTCSCGWSRIP----RIASP--TNEEAV 284

  Fly   945 FGEYPWHVAILKKDPKESIYACGGTLIDAQHIISAAHCI---KSQNGFDLRVRLGEWDVNHDVEF 1006
            ..|:|....:|.|  |.....||..:|..::::|||||.   ::.:...|||.:||.|:....|.
  Fly   285 LHEFPPMAGVLTK--KHGKVFCGAAIIHHRYLLSAAHCFLGPETNSAAKLRVVVGEHDLASSFET 347

  Fly  1007 FPYIERDVVSVHIHPEY--YAGTLDNDLAVLKLDQPVDFTKNPHISPACLPDKYSD------FTG 1063
            |.....|:.::.:|.::  .:|...||:|:||....:.:::  |:.|||||.:..:      ..|
  Fly   348 FATQRYDLDALILHEDFSQASGQPKNDIAMLKTRMAIVWSQ--HVGPACLPLQPGEDGQKLPLAG 410

  Fly  1064 ARCWTTGWGKDAFGEHGKYQNILKEVDVPILSHQQCESQLRNTRLGYSYKLNPGFVCAGG----- 1123
            .:....|||..::|  |...:.|.:..:.::..::|...|.:               |||
  Fly   411 HQVVAAGWGTTSYG--GPQTHRLLKATLDVIDGRRCRQALSS---------------AGGLPPHT 458

  Fly  1124 ----EEGKDACKGDGGGPLVCDRNGAMHVVGVVSWGIGCGQVNVPGVYVKVSAYLPWIQ 1178
                ..|:|.|:.|.||.|....||.:..||:||:|..|. ...|.|..:|::::.||:
  Fly   459 FCTYTPGRDTCQYDSGGALYERINGRLMAVGIVSFGQACA-AQQPSVNTRVASFIKWIR 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4998	NP_001036609.1	Tryp_SPc	942..1180	CDD:238113	67/257 (26%)
CG4998	NP_001036609.1	Tryp_SPc	942..1177	CDD:214473	65/254 (26%)
CG14760	NP_610366.1	CUB	37..126	CDD:294042	16/93 (17%)
		Tryp_SPc	281..516	CDD:238113	66/256 (26%)
		Tryp_SPc	281..515	CDD:214473	65/255 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456038
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24258
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940