DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4950 and AT5G23400

DIOPT Version :9

Sequence 1:	NP_001261934.1	Gene:	CG4950 / 39783	FlyBaseID:	FBgn0036587	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_197731.1	Gene:	AT5G23400 / 832405	AraportID:	AT5G23400	Length:	589	Species:	Arabidopsis thaliana

Alignment Length:	606	Identity:	139/606 - (22%)
Similarity:	235/606 - (38%)	Gaps:	172/606 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 DSMGYMD----------------VNEAFCTVTGFTVTHSQNVVIKNIPPGNMVKFMKFYESTLLY 84
            |:.|.:|                .|.|...|||..:..:.|                  |.| ||
plant    49 DTTGVLDSWVGKDCCNGDWEGVQCNPATGKVTGLVLQSAVN------------------EPT-LY 94

  Fly    85 MPFHLFETFPYLKTLDVSNTNILELTRNAFSAASNLTYLNLAYNNLTSIQTSVF----IGANVLM 145
            |...|..:...|::|:     :|.:|.|.|...|    :..:::||||::..:.    :..|||.
plant    95 MKGTLSPSLGNLRSLE-----LLLITGNKFITGS----IPNSFSNLTSLRQLILDDNSLQGNVLS 150

  Fly   146 RL-DLSYNEISSLSVNAFCGLHTISQIYLTGNLLKELHNDIFKDNEYLEKVSFEGNLLTSIQPEV 209
            .| .|...||.||:.|.|.||...|    .|:|.:....::.::       ||.|.:     |..
plant   151 SLGHLPLLEILSLAGNRFSGLVPAS----FGSLRRLTTMNLARN-------SFSGPI-----PVT 199

  Fly   210 FRNMRRIKEVNLSNNRLIFIHPDTFADAASLENLVLSYN--------------ELKNFQLTEKNI 260
            |:|:.:::.::||:|.|....||......:|.||.||.|              :|:...|....:
plant   200 FKNLLKLENLDLSSNLLSGPIPDFIGQFQNLTNLYLSSNRFSGVLPVSVYSLRKLQTMSLERNGL 264

  Fly   261 VHQLHLDNNY---LTNLTINATRFVRASHNQISELFLHQSLHIETLDLSANKLSS---ISNITNI 319
            ...|....:|   ||:|.::..:|:......|:.|   |:|.  :|:||.|..|.   :......
plant   265 TGPLSDRFSYLKSLTSLQLSGNKFIGHIPASITGL---QNLW--SLNLSRNLFSDPLPVVGARGF 324

  Fly   320 THMLYLDVSDNPIGPLNISTFSQLKRLRGLNLRGTGIRELKFGMFSKQKYLEELDLSFNNLTILN 384
            ..:|.:|:|.|.:....|.::.:.|:|..:||.|..:|. .|...::...|..||||.|.|| .:
plant   325 PSLLSIDLSYNNLNLGAIPSWIRDKQLSDINLAGCKLRG-TFPKLTRPTTLTSLDLSDNFLT-GD 387

  Fly   385 LDMFVPYLTNLKKFLIDGNGLTELQGNRTFSEAFPQLQKLGVSRNRFNCSYLHHLLIPPSLPESV 449
            :..|:..|||::|.                        ||..::.||:.|.|       .|||.|
plant   388 VSAFLTSLTNVQKV------------------------KLSKNQLRFDLSKL-------KLPEGV 421

  Fly   450 VLNIEPDTNL----------DETPHIRDVSCISQSQ--------------EVVNASFTAEESKLE 490
            . :|:..:||          ::|....:...::.:|              :|:|........::.
plant   422 A-SIDLSSNLVTGSLSSLINNKTSSFLEEIHLTNNQISGRIPDFGESLNLKVLNIGSNKISGQIP 485

  Fly   491 SQIQMLSK--QLDIVGSHSKNLELHLAFMQIFAYVMGGLVLVGVVSLITLRYLK---NQRSGRYD 550
            |.|..|.:  :|||..:|                :.|| :...:..|..|::|.   |..:||..
plant   486 SSISNLVELVRLDISRNH----------------ITGG-IPQAIGQLAQLKWLDLSINALTGRIP 533

  Fly   551 RSSIVFRS--NATMEANLTLG 569
            .|.:..::  :|:..||...|
plant   534 DSLLNIKTIKHASFRANRLCG 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4950	NP_001261934.1	leucine-rich repeat	96..119	CDD:275380	6/22 (27%)
		LRR_8	118..178	CDD:290566	20/64 (31%)
		leucine-rich repeat	120..143	CDD:275380	4/26 (15%)
		leucine-rich repeat	144..167	CDD:275380	11/23 (48%)
		leucine-rich repeat	168..191	CDD:275380	3/22 (14%)
		LRR_8	192..250	CDD:290566	18/71 (25%)
		leucine-rich repeat	192..215	CDD:275380	6/22 (27%)
		LRR_RI	<207..432	CDD:238064	60/244 (25%)
		leucine-rich repeat	216..239	CDD:275380	6/22 (27%)
		leucine-rich repeat	240..299	CDD:275380	17/75 (23%)
		LRR_8	299..356	CDD:290566	15/59 (25%)
		leucine-rich repeat	300..321	CDD:275380	5/23 (22%)
		leucine-rich repeat	322..345	CDD:275380	5/22 (23%)
		LRR_8	344..405	CDD:290566	20/60 (33%)
		leucine-rich repeat	346..365	CDD:275380	6/18 (33%)
		leucine-rich repeat	370..394	CDD:275380	10/23 (43%)
		leucine-rich repeat	395..420	CDD:275380	1/24 (4%)
AT5G23400	NP_197731.1	PLN00113	39..>557	CDD:215061	139/606 (23%)
		leucine-rich repeat	109..133	CDD:275380	8/32 (25%)
		leucine-rich repeat	134..157	CDD:275380	5/22 (23%)
		leucine-rich repeat	158..181	CDD:275380	11/26 (42%)
		leucine-rich repeat	182..205	CDD:275380	6/34 (18%)
		leucine-rich repeat	206..229	CDD:275380	6/22 (27%)
		leucine-rich repeat	230..253	CDD:275380	6/22 (27%)
		leucine-rich repeat	254..277	CDD:275380	4/22 (18%)
		leucine-rich repeat	278..301	CDD:275380	6/25 (24%)
		leucine-rich repeat	302..326	CDD:275380	6/25 (24%)
		leucine-rich repeat	374..397	CDD:275380	10/23 (43%)
		leucine-rich repeat	398..440	CDD:275380	14/73 (19%)
		leucine-rich repeat	447..469	CDD:275380	1/21 (5%)
		leucine-rich repeat	470..493	CDD:275380	5/22 (23%)
		leucine-rich repeat	494..517	CDD:275380	7/39 (18%)
		leucine-rich repeat	518..536	CDD:275380	5/17 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910