DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4950 and RLP31

DIOPT Version :9

Sequence 1:	NP_001261934.1	Gene:	CG4950 / 39783	FlyBaseID:	FBgn0036587	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_187188.2	Gene:	RLP31 / 819701	AraportID:	AT3G05370	Length:	860	Species:	Arabidopsis thaliana

Alignment Length:	633	Identity:	138/633 - (21%)
Similarity:	232/633 - (36%)	Gaps:	138/633 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 GDIPLRCDEYDSMGYM---------DVNEAFCTVTGFTVTHSQNVVIKNIPPGNMVKFMKF---- 77
            |.:|........:.|:         ::...|..:|...|.:..|...:::.|.:|..|...
plant   170 GQLPASIGNLTQLEYLIFSHNKFSGNIPVTFSNLTKLLVVNLYNNSFESMLPLDMSGFQNLDYFN 234

  Fly    78 -----YESTLLYMPFHLFETFPYLKTLDVSNTNI---LELTRNAFSAASNLTYLNLAYNNLTSIQ 134
                 :..||   |..|| |.|.|:..::.....   :|. ||.:|.::.|.||.|:.|......
plant   235 VGENSFSGTL---PKSLF-TIPSLRWANLEGNMFKGPIEF-RNMYSPSTRLQYLFLSQNKFDGPI 294

  Fly   135 TSVFIGANVLMRLDLSYNEISSLSVNAFCGLHTISQIYLTGNLLK---ELHNDIFKDNEYLEKVS 196
            .........|:.||||:|.::.........:.|:.::.|.||.||   |..|  ...:..|:.::
plant   295 PDTLSQYLNLIELDLSFNNLTGSFPTFLFTIPTLERVNLEGNHLKGPVEFGN--MSSSSSLKFLN 357

  Fly   197 FEGNLLTSIQPEVFRNMRRIKEVNLSNNRLIFIHPDTFADAASLENLVLSYNELKNFQLTEKNIV 261
            |..|......||.......::|::||.|..|...|.:.:..|.||          .|.|.:.|:|
plant   358 FAQNEFNGSIPESVSQYLNLEELHLSFNNFIGTIPRSISKLAKLE----------YFCLEDNNMV 412

  Fly   262 HQLHLDNNYLTNLTINATRFVRASHNQISELFLHQS-----LHIETLDLSANKLSS-----ISNI 316
            .::   .::|..||:     |..|:|..:. |...|     ..::.||||:|....     |..:
plant   413 GEV---PSWLWRLTM-----VALSNNSFNS-FGESSEGLDETQVQWLDLSSNSFQGPFPHWICKL 468

  Fly   317 TNITHMLYLDVSDNPIGPLNISTFSQLKRLRGLNLRGTGIRELKFGMFSKQKYLEELDLSFNNL- 380
            .::..::..|...|...|..:|:|  :..|..|.||...:......:|.....|..||:|.|.|
plant   469 RSLEILIMSDNRFNGSIPPCLSSF--MVSLTDLILRNNSLSGPLPDIFVNATKLLSLDVSRNKLD 531

  Fly   381 -------------TILNL------DMFVPYLTNLKKF--LIDGNGLTELQGNRTF--------SE 416
                         .:||:      |.|..:|.:|...  ||       |:.|..:        |.
plant   532 GVLPKSLIHCKAMQLLNVRSNKIKDKFPSWLGSLPSLHVLI-------LRSNEFYGTLYQPHASI 589

  Fly   417 AFPQLQKLGVSRNRFNCSYLHHLLIPPSLPE---------SVVLNIEPDTNLDETPHIRDV---- 468
            .|..|:.:.||         |:.|| .:||.         |.:...:.|..|.|.|::..|
plant   590 GFQSLRVIDVS---------HNDLI-GTLPSFYFSSWREMSRLTGEDGDFRLSEAPYMGKVLNAT 644

  Fly   469 SCISQSQEVVNASFTAEESKLESQIQMLSKQLDIVGS-------HSKNLELHLAFMQIFAYVMGG 526
            :....|.|:||.....|..::..:    :|.::..|:       .|..|...|..:.:.:....|
plant   645 AFFVDSMEIVNKGVETEFKRINEE----NKVINFSGNRFSGNIPESIGLLKELRHLNLSSNAFTG 705

  Fly   527 LVLVGVVSLITLRYLK---NQRSGRYDR--SSIVFRSNATMEANLTLG 569
            .:...:.:|:.|..|.   ||.||:..:  .|:.|.|......|...|
plant   706 NIPQSLANLMKLEALDLSLNQLSGQIPQGLGSLSFMSTMNFSYNFLEG 753

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4950	NP_001261934.1	leucine-rich repeat	96..119	CDD:275380	5/25 (20%)
		LRR_8	118..178	CDD:290566	15/59 (25%)
		leucine-rich repeat	120..143	CDD:275380	5/22 (23%)
		leucine-rich repeat	144..167	CDD:275380	6/22 (27%)
		leucine-rich repeat	168..191	CDD:275380	7/25 (28%)
		LRR_8	192..250	CDD:290566	14/57 (25%)
		leucine-rich repeat	192..215	CDD:275380	5/22 (23%)
		LRR_RI	<207..432	CDD:238064	60/264 (23%)
		leucine-rich repeat	216..239	CDD:275380	6/22 (27%)
		leucine-rich repeat	240..299	CDD:275380	14/63 (22%)
		LRR_8	299..356	CDD:290566	15/61 (25%)
		leucine-rich repeat	300..321	CDD:275380	6/25 (24%)
		leucine-rich repeat	322..345	CDD:275380	5/22 (23%)
		LRR_8	344..405	CDD:290566	19/82 (23%)
		leucine-rich repeat	346..365	CDD:275380	4/18 (22%)
		leucine-rich repeat	370..394	CDD:275380	11/43 (26%)
		leucine-rich repeat	395..420	CDD:275380	7/34 (21%)
RLP31	NP_187188.2	leucine-rich repeat	422..446	CDD:275380	7/29 (24%)
		leucine-rich repeat	447..470	CDD:275380	6/22 (27%)
		leucine-rich repeat	471..495	CDD:275380	5/25 (20%)
		leucine-rich repeat	496..519	CDD:275380	5/22 (23%)
		leucine-rich repeat	520..543	CDD:275380	6/22 (27%)
		leucine-rich repeat	544..565	CDD:275380	5/20 (25%)
		leucine-rich repeat	568..593	CDD:275380	6/31 (19%)
		leucine-rich repeat	594..621	CDD:275380	8/36 (22%)
		leucine-rich repeat	622..692	CDD:275380	14/73 (19%)
		PLN00113	<681..758	CDD:331614	16/73 (22%)
		leucine-rich repeat	693..716	CDD:275380	3/22 (14%)
		leucine-rich repeat	717..738	CDD:275380	6/20 (30%)
		LRRNT_2	33..78	CDD:311940
		PLN00113	60..>610	CDD:331614	108/484 (22%)
		leucine-rich repeat	86..109	CDD:275380
		leucine-rich repeat	110..133	CDD:275380
		leucine-rich repeat	134..157	CDD:275380
		leucine-rich repeat	158..181	CDD:275380	2/10 (20%)
		leucine-rich repeat	182..205	CDD:275380	2/22 (9%)
		leucine-rich repeat	206..229	CDD:275380	5/22 (23%)
		leucine-rich repeat	230..253	CDD:275380	6/26 (23%)
		leucine-rich repeat	254..279	CDD:275380	5/25 (20%)
		leucine-rich repeat	280..303	CDD:275380	5/22 (23%)
		leucine-rich repeat	328..376	CDD:275380	12/49 (24%)
		leucine-rich repeat	377..398	CDD:275380	6/20 (30%)
		leucine-rich repeat	401..421	CDD:275380	7/32 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000