DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4950 and AT2G26380

DIOPT Version :9

Sequence 1:	NP_001261934.1	Gene:	CG4950 / 39783	FlyBaseID:	FBgn0036587	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_180206.1	Gene:	AT2G26380 / 817178	AraportID:	AT2G26380	Length:	480	Species:	Arabidopsis thaliana

Alignment Length:	469	Identity:	113/469 - (24%)
Similarity:	164/469 - (34%)	Gaps:	185/469 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 HSQNVV---IKNIPPGNMVKFMKFYESTLLYMPFHLFETFPYLKTLDVSNT--------NILELT 110
            |.:.||   :|||              |..:.|| ||. .|:||.:.:.||        ||..|.
plant   104 HLEGVVFINLKNI--------------TGPFPPF-LFR-LPHLKYVYLENTRLSGPLPANIGALN 152

  Fly   111 R--------NAF-----SAASNLT---YLNLAYNNLTSIQTSVFIGANVLMRLDLSYNEISSLSV 159
            |        |.|     |:.||||   ||||..|.||.   ::.:|
plant   153 RLDTLTVKGNRFIGSIPSSISNLTRLNYLNLGGNLLTG---TIPLG------------------- 195

  Fly   160 NAFCGLHTISQIYLTGNLLKELHNDIFKDNEYLEKVSFEGNLLTSIQPEVFRNMRRIKEVNLSNN 224
                    |:.:.|..||                  :.:||.|:...|::|::|..::.:.||.|
plant   196 --------IANLKLISNL------------------NLDGNRLSGTIPDIFKSMTNLRILTLSRN 234

  Fly   225 RLIFIHPDTFADAASLENLVLSYNELKNFQLTEKNIVHQLHLDNNYLTNLTINATRFVRASHNQI 289
            |.....|.:.|..|.    ||::.||.               .||...::....:|||.
plant   235 RFSGKLPPSIASLAP----VLAFLELG---------------QNNLSGSIPSYLSRFVA------ 274

  Fly   290 SELFLHQSLHIETLDLSAN-----------KLSSISNITNITHMLYLDVSDNPIGPLNISTF--- 340
                      ::|||||.|           ||:.|:|| |::|.|.    .||...||:..:
plant   275 ----------LDTLDLSKNRFSGAVPKSLAKLTKIANI-NLSHNLL----TNPFPVLNVKNYILT 324

  Fly   341 -----------------SQLKRLRGLNLRGTGIRELKFGMFSKQKYL-EELDLSFNNLTILNLDM 387
                             :....|..|.|...||:.......::|..| ..:|||.|.::...| .
plant   325 LDLSYNKFHMETIPEWVTSASILGSLKLAKCGIKMSLDDWKTRQTDLYVSIDLSDNEISGSPL-R 388

  Fly   388 FVPYLTNLKKFLIDGNGLTELQGNRTFSEAFPQLQKLGVSRN--------------RFNCSYLHH 438
            |:.....|::|.:.||.|.......:||..   |:.|.:|||              ..|.|. :|
plant   389 FLKGAEQLREFRMSGNKLRFDLRKLSFSTT---LETLDLSRNLVFGKVPARVAGLKTLNLSQ-NH 449

  Fly   439 L---LIPPSLPESV 449
            |   |.....||||
plant   450 LCGKLPVTKFPESV 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4950	NP_001261934.1	leucine-rich repeat	96..119	CDD:275380	11/43 (26%)
		LRR_8	118..178	CDD:290566	15/62 (24%)
		leucine-rich repeat	120..143	CDD:275380	10/25 (40%)
		leucine-rich repeat	144..167	CDD:275380	0/22 (0%)
		leucine-rich repeat	168..191	CDD:275380	4/22 (18%)
		LRR_8	192..250	CDD:290566	15/57 (26%)
		leucine-rich repeat	192..215	CDD:275380	6/22 (27%)
		LRR_RI	<207..432	CDD:238064	62/270 (23%)
		leucine-rich repeat	216..239	CDD:275380	6/22 (27%)
		leucine-rich repeat	240..299	CDD:275380	9/58 (16%)
		LRR_8	299..356	CDD:290566	21/87 (24%)
		leucine-rich repeat	300..321	CDD:275380	12/31 (39%)
		leucine-rich repeat	322..345	CDD:275380	5/42 (12%)
		LRR_8	344..405	CDD:290566	17/61 (28%)
		leucine-rich repeat	346..365	CDD:275380	5/18 (28%)
		leucine-rich repeat	370..394	CDD:275380	7/24 (29%)
		leucine-rich repeat	395..420	CDD:275380	7/24 (29%)
AT2G26380	NP_180206.1	LRRNT_2	30..69	CDD:285463
		leucine-rich repeat	102..129	CDD:275380	11/40 (28%)
		leucine-rich repeat	130..153	CDD:275380	7/22 (32%)
		LRR_8	153..212	CDD:290566	22/106 (21%)
		leucine-rich repeat	154..177	CDD:275380	6/22 (27%)
		LRR_RI	<163..420	CDD:238064	78/348 (22%)
		leucine-rich repeat	178..201	CDD:275380	9/52 (17%)
		leucine-rich repeat	202..225	CDD:275380	8/40 (20%)
		LRR_8	204..261	CDD:290566	20/93 (22%)
		leucine-rich repeat	226..250	CDD:275380	7/27 (26%)
		leucine-rich repeat	251..274	CDD:275380	7/37 (19%)
		leucine-rich repeat	275..298	CDD:275380	8/22 (36%)
		leucine-rich repeat	322..360	CDD:275380	5/37 (14%)
		leucine-rich repeat	361..395	CDD:275380	8/34 (24%)
		leucine-rich repeat	419..439	CDD:275380	5/19 (26%)
		leucine-rich repeat	440..466	CDD:275380	9/25 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000