Protein Alignment CG4950 and LOC5666907

DIOPT Version :10

• Sequence 1: NP_648855.2
• Gene: CG4950 / 39783
• FlyBaseID: FBgn0036587
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: XP_061496525.1
• Gene: LOC5666907 / 5666907
• VectorBaseID: AGAMI1_000379
• Length: 1776
• Species: Anopheles gambiae
• Alignment Length: 517
• Identity: 111/517 - (21%)
• Similarity: 210/517 - (40%)
• Gaps: 113/517 - (21%)

  Fly    26 GDIPLRCDEYDSMGYMDVNEAFCTVTGFTVTHSQNVVIKNIPPGNMVKFMKFYESTLLYMPFHLF 90
            |::...|..||....|...:.:......|:.:.:||..||              ||:..:|..|.
Mosquito  1205 GNLQYDCVFYDVHIDMQTQDVYFGFEDMTLNNQKNVTFKN--------------STMRKLPAALL 1255

  Fly    91 ETFPYLKTLDVSNTNILELTRNAFSAASNLTYLNLAYNNLTSIQTSVFIGANVLMRLDLSYNEIS 155
            .:|..::.|::::..|.|:..|||:.|
Mosquito  1256 ASFRQVELLNLNDLQIEEIDTNAFAYA-------------------------------------- 1282

  Fly   156 SLSVNAFCGLHTISQIYLTGNLLKELHNDIFKDNEYLEKVSFEGNLLTSIQPEVFRNMRRIKEVN 220
                      |||.::|:..|.::.|...:|::...|..:..|.|.|.|:...:|.|..::..:.
Mosquito  1283 ----------HTIQKLYMGFNAIRYLPPYVFQNVPLLTVLVLERNDLISLPRGIFHNTPKLSMLA 1337

  Fly   221 LSNNRLIFIHPDTFADAASLENLVLSYNELKNFQLTEKNIVHQLHLDNNYLTNLTIN-ATRFVRA 284
            :|||.|..|..|||.....|:||.||.|.|.:..|.....:..:::..|.|:.|.|. |...:.|
Mosquito  1338 MSNNNLERIEDDTFQATTELQNLQLSSNRLTHVDLALIPSLFHVNVSYNLLSTLAIPIAVEELDA 1402

  Fly   285 SHNQISELFLHQSLHIETLDLSANKLSSISNITNITHMLYLDVSDNPIGPLNISTFSQLKRLR-- 347
            |||.|:.:....::.:..|.|..|.|:..:.:.|...::.:|:|.|.:..:....|.:::||.
Mosquito  1403 SHNTINVVRGPVNVELTILKLQHNNLTDTAWLLNYPGLVDVDLSYNQLEKITYQHFVKMQRLERL 1467

  Fly   348 --------GLNLRGTGIRELKFGMFSKQKYLEELDLSFNNLTILNLDMFVPYLTNLKKFLIDGNG 404
                    .|||.|..|..||.           ||||.|:|  |:::...|....::...:|.|.
Mosquito  1468 YVSNNHLVALNLYGQPIPTLKV-----------LDLSHNHL--LHVERNQPQFDRVEYLYLDHNS 1519

  Fly   405 LTELQGNRTFSEAFPQLQKLGVSRNRFNCSYLHHLLIPPSLPESVVLNIEPDTNLD--------- 460
            :..|:.:.:.:     |:.|.:|.|.::|:.|..|.  .::..|.|.:.:....:|
Mosquito  1520 IVTLKLSTSHT-----LKNLTLSHNDWDCNSLRALF--RNVAHSAVHDADQHCKIDYQLEHGLCC 1577

  Fly   461 ---ETPH----IRDVSCISQSQEVVNA----SFTAEESKLESQIQMLSKQLDIVGSHSKNLE 511
               :.|:    ::.::..|.::::..|    |.|...:.::|....:::|.|:....::.||
Mosquito  1578 KESDKPYLDRLLQYIALTSVAEKLQRAQGRCSATDAINSVQSLSHYITQQGDVPLQGNEQLE 1639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4950	NP_648855.2	LRR	96..411	CDD:443914	76/325 (23%)
		leucine-rich repeat	96..119	CDD:275380	7/22 (32%)
		leucine-rich repeat	120..143	CDD:275380	0/22 (0%)
		leucine-rich repeat	144..167	CDD:275380	0/22 (0%)
		leucine-rich repeat	168..191	CDD:275380	5/22 (23%)
		leucine-rich repeat	192..215	CDD:275380	7/22 (32%)
		leucine-rich repeat	216..239	CDD:275380	8/22 (36%)
		leucine-rich repeat	240..299	CDD:275380	18/59 (31%)
		leucine-rich repeat	300..321	CDD:275380	5/20 (25%)
		leucine-rich repeat	322..345	CDD:275380	4/22 (18%)
		leucine-rich repeat	346..365	CDD:275380	8/28 (29%)
		leucine-rich repeat	370..394	CDD:275380	8/23 (35%)
		leucine-rich repeat	395..420	CDD:275380	3/24 (13%)
LOC5666907	XP_061496525.1	None