DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4950 and CG7896

DIOPT Version :9

Sequence 1:NP_001261934.1 Gene:CG4950 / 39783 FlyBaseID:FBgn0036587 Length:574 Species:Drosophila melanogaster
Sequence 2:NP_651754.1 Gene:CG7896 / 43552 FlyBaseID:FBgn0039728 Length:1392 Species:Drosophila melanogaster


Alignment Length:598 Identity:137/598 - (22%)
Similarity:246/598 - (41%) Gaps:136/598 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    54 TVTHSQNVVIKNIPPGNMVKFMKFY--------------------ESTLLYM------------- 85
            |::.|:| ||:.:|||:...|...:                    ||||:.:             
  Fly   430 TLSLSRN-VIRELPPGSFQMFSSLHTLDLSGNSLAVINADTFAGLESTLMALKLSQNRLTGLGGA 493

  Fly    86 PFHLFETFPYLKTLDVSNTNILELTRNAFSAASNLTYLNLAYNNLTSIQTSVFIGANVLMRLDLS 150
            |:.|    |.|::||:|...:.||....|....|:..|||:.|:||.:..::|...:.|..:|||
  Fly   494 PWVL----PELRSLDLSGNTLTELPSTIFEELENVQSLNLSGNHLTPLTGALFKPLDRLQVIDLS 554

  Fly   151 YNEISSLSVNAFCGLHTISQIYLTGNLLKELHNDIFKDNEYLEKVSFEGNLLTSIQPEVFRNMRR 215
            ...|..:|.:...||..:..|||..|.|:||.:..|.:...:..:....|.:.||:...|.|:.:
  Fly   555 GCNIRQISGDLLAGLQDLKHIYLNDNQLQELQDGSFVNLWNISSIDLSNNRIGSIRSGAFVNVMK 619

  Fly   216 IKEVNLSNNRLIFIHPDTFADAASLENLVLSYNEL-----KNFQLTEKNIVHQLHLDNNYLTNL- 274
            :::::|..|:|.....:.|.....:|.|.:|.|:|     .:|::..:  :.::...||..:.. 
  Fly   620 LQKLDLHGNQLSAFKGEYFNTGTGIEELDISDNQLSYLFPSSFRIHPR--LREIRAANNKFSFFP 682

  Fly   275 -----TINATRFVRASHNQ---ISELFLHQSLHIETLDLSANKLSSISNIT--NITHMLYLDVSD 329
                 |:.....:..||||   |.||...:...:..|.::.|:|..:|.:.  |.|.:..||::.
  Fly   683 AELISTLQYLEHIDLSHNQLKTIEELDFARLPRLRVLLVANNQLDMVSEMAFHNSTQLQILDLAH 747

  Fly   330 NPIGPLNISTFSQLKRLRGLNLRGTGIRELKFGMFSKQK--YLEELDLSFNNLTILNLDMFVPYL 392
            |.:..:...||..|.||..|||.|..:.||..|:|.:.|  .||.::|:.|......|:......
  Fly   748 NNLDRIGERTFEGLVRLEQLNLEGNRLSELSDGVFERTKLQMLENINLAHNRFEYAPLNALQRQF 812

  Fly   393 TNLKKFLIDGNGLTELQGNRTFSEAFPQLQKLGVSRNRFNCSYLHHLLIPP-------------- 443
            ..:....:..|.:.||.|:   ......::::.:|.|..:...:|::|..|              
  Fly   813 FFVSSVDLSHNKIKELPGD---DSIMVNIKRIDLSFNPLSSKAVHNVLNEPKTVRELSLAGTGIE 874

  Fly   444 -------------SLPESVVLNIEP------------DTNLDETPHIRDVSC------ISQSQEV 477
                         :|..:.:.|::|            |.:.::...:.|:|.      :.||.:|
  Fly   875 NLELLETPFLQFLNLSHNKLKNVKPEVFQRVTLLETLDLSSNQLESLEDLSMAWPQLQVLQSLDV 939

  Fly   478 VNASFTAEESKLESQIQMLSKQLDIVGSHSKNLEL-HL---------AFMQ------IFAY---V 523
            .|.||.........:::||           ::|.| ||         ||.|      :.||   :
  Fly   940 SNNSFEIVSQSNFGKLEML-----------RSLRLSHLPQCTRIEKNAFKQLPNLVSLEAYDLPL 993

  Fly   524 MGGLVLVGVVSLI 536
            :|.|.|.|::.|:
  Fly   994 LGYLDLQGILELL 1006

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4950NP_001261934.1 leucine-rich repeat 96..119 CDD:275380 7/22 (32%)
LRR_8 118..178 CDD:290566 20/59 (34%)
leucine-rich repeat 120..143 CDD:275380 7/22 (32%)
leucine-rich repeat 144..167 CDD:275380 8/22 (36%)
leucine-rich repeat 168..191 CDD:275380 8/22 (36%)
LRR_8 192..250 CDD:290566 13/57 (23%)
leucine-rich repeat 192..215 CDD:275380 5/22 (23%)
LRR_RI <207..432 CDD:238064 56/242 (23%)
leucine-rich repeat 216..239 CDD:275380 4/22 (18%)
leucine-rich repeat 240..299 CDD:275380 16/72 (22%)
LRR_8 299..356 CDD:290566 18/58 (31%)
leucine-rich repeat 300..321 CDD:275380 5/22 (23%)
leucine-rich repeat 322..345 CDD:275380 6/22 (27%)
LRR_8 344..405 CDD:290566 17/62 (27%)
leucine-rich repeat 346..365 CDD:275380 8/18 (44%)
leucine-rich repeat 370..394 CDD:275380 5/23 (22%)
leucine-rich repeat 395..420 CDD:275380 4/24 (17%)
CG7896NP_651754.1 LRR_8 109..172 CDD:290566
leucine-rich repeat 109..132 CDD:275380
LRR_RI <132..338 CDD:238064
leucine-rich repeat 133..161 CDD:275380
LRR_8 160..220 CDD:290566
leucine-rich repeat 162..185 CDD:275380
leucine-rich repeat 186..209 CDD:275380
leucine-rich repeat 210..233 CDD:275380
LRR_8 232..290 CDD:290566
leucine-rich repeat 234..257 CDD:275380
leucine-rich repeat 258..281 CDD:275380
LRR_RI 273..535 CDD:238064 28/109 (26%)
LRR_8 281..338 CDD:290566
leucine-rich repeat 282..329 CDD:275380
LRR_8 328..388 CDD:290566
leucine-rich repeat 330..353 CDD:275380
leucine-rich repeat 354..377 CDD:275380
leucine-rich repeat 378..401 CDD:275380
leucine-rich repeat 402..425 CDD:275380
leucine-rich repeat 428..451 CDD:275380 9/21 (43%)
LRR_8 429..487 CDD:290566 13/57 (23%)
leucine-rich repeat 452..473 CDD:275380 0/20 (0%)
leucine-rich repeat 477..497 CDD:275378 2/19 (11%)
LRR_8 498..558 CDD:290566 20/59 (34%)
leucine-rich repeat 500..523 CDD:275380 7/22 (32%)
LRR_RI 502..769 CDD:238064 70/268 (26%)
leucine-rich repeat 524..547 CDD:275380 7/22 (32%)
leucine-rich repeat 548..571 CDD:275380 8/22 (36%)
LRR_8 572..630 CDD:290566 15/57 (26%)
leucine-rich repeat 572..595 CDD:275380 8/22 (36%)
leucine-rich repeat 596..619 CDD:275380 5/22 (23%)
LRR_8 619..678 CDD:290566 12/60 (20%)
leucine-rich repeat 620..643 CDD:275380 4/22 (18%)
leucine-rich repeat 644..667 CDD:275380 6/22 (27%)
LRR_8 666..726 CDD:290566 12/61 (20%)
leucine-rich repeat 668..691 CDD:275380 3/22 (14%)
leucine-rich repeat 692..715 CDD:275380 7/22 (32%)
LRR_8 714..774 CDD:290566 18/59 (31%)
leucine-rich repeat 716..739 CDD:275380 5/22 (23%)
leucine-rich repeat 740..761 CDD:275380 5/20 (25%)
leucine-rich repeat 764..789 CDD:275380 10/24 (42%)
leucine-rich repeat 790..810 CDD:275380 5/19 (26%)
leucine-rich repeat 818..850 CDD:275380 6/34 (18%)
leucine-rich repeat 863..883 CDD:275378 0/19 (0%)
LRR_RI <878..1070 CDD:238064 28/140 (20%)
LRR_8 884..944 CDD:290566 10/59 (17%)
LRR_4 884..925 CDD:289563 5/40 (13%)
leucine-rich repeat 884..907 CDD:275380 3/22 (14%)
leucine-rich repeat 908..933 CDD:275380 3/24 (13%)
leucine-rich repeat 934..955 CDD:275380 6/20 (30%)
leucine-rich repeat 958..982 CDD:275380 8/34 (24%)
leucine-rich repeat 983..1055 CDD:275380 7/24 (29%)
leucine-rich repeat 1009..1033 CDD:275380
leucine-rich repeat 1058..1085 CDD:275380
TPKR_C2 1121..1168 CDD:301599
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45453763
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.840

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