Protein Alignment CG4950 and alrm

DIOPT Version :10

• Sequence 1: NP_648855.2
• Gene: CG4950 / 39783
• FlyBaseID: FBgn0036587
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_651393.1
• Gene: alrm / 43074
• FlyBaseID: FBgn0039332
• Length: 471
• Species: Drosophila melanogaster
• Alignment Length: 528
• Identity: 133/528 - (25%)
• Similarity: 225/528 - (42%)
• Gaps: 87/528 - (16%)

  Fly     7 ILEVIVILILAIS-----SCDGSGGDIPLRCDEYDSMGYMDVNEAFCTVTGFTVTHSQNVVIKNI 66
            :|.:.|:|||..|     ...|||....|...::.|.|       .|  |...:..|..|::...
  Fly     7 LLSLQVVLILPPSYHLATPSSGSGQLRRLWLQDHCSAG-------IC--TNVVIGRSDYVILSQA 62

  Fly    67 PPGNMVKFMKFYESTLLYMPFHLFETFPYLKTLDVSNTNILELTRNAFSAASNLTYLNLAYNNLT 131
            |.|. ...:.|..|::..:|..||:|||.|:.|.:.|.::....:..|..||||..|.|.||.|.
  Fly    63 PIGG-TTMLTFLNSSIAKIPHLLFDTFPDLQVLRMENCSLETFEKPQFEGASNLMSLFLGYNRLK 126

  Fly   132 SIQTSVFIGANVLMRLDLSYNEISSLSVNAFCGLHTISQIYLTGNLLKELHNDIFKDNEYLEKVS 196
            .|..::|:||:                        .::.::|.||.||:|.|..|...:.::::|
  Fly   127 DIPKNIFLGAD------------------------NLATLHLQGNQLKQLGNHSFHALKEVKELS 167

  Fly   197 FEGNLLTSIQPEVFRNMRRIKEVNLSNNRLIFIHPDTFADAASLENLVLSYNELKNFQ---LTEK 258
            ...|.|..|...||..||::.::||:.|||..:....|....:|..|.|:.|....|:   |..:
  Fly   168 LAENQLEQISLGVFSGMRKLMDLNLAGNRLDALPRGVFDRNLNLTKLNLARNRFTAFESELLKLQ 232

  Fly   259 NIVHQLHLDNNYLTNLTINATRF-VRASHN-QISELFLHQSLHIETLDLSANKLSSISNITNITH 321
            .:..||.:..|....||:|.|.. |..:|: .:..|.::..:|  .|||..|.|..:.:|....:
  Fly   233 PVFTQLDISGNIFQELTLNFTMLDVAIAHSCDLRRLTVYGVIH--ELDLHNNSLREMPHIPLAAN 295

  Fly   322 MLYLDVSDNPIGPLNISTFSQLKRLRGLNLRGTGIRELKFGMFSKQKYLEELDLSFNNLTILNLD 386
            :..||:|.||:|.|..:...:...|..|||..||..||..|:|.||.:|:.||:|.|::..|.:.
  Fly   296 VSSLDLSHNPLGNLQGNPLRRFTSLLRLNLSATGAHELPEGLFKKQSHLQMLDISGNSIYSLKIT 360

  Fly   387 MFVPYLTNLKKFLIDGNGLTELQGNRTFSEAFPQLQKLGVSRNRFNCSYLHHLLIPPSLPESVVL 451
            :|                           ::...||.....:|.:||.:|.  |:..|..:...:
  Fly   361 IF---------------------------DSLKALQYFYFQQNNWNCDFLQ--LLMSSFVKRKDI 396

  Fly   452 NIEPDTNLDE--TPHIRDVSCISQSQEVVNASFTAEESKLESQIQMLSKQLDIVGSHSKNLE--L 512
            :...|....|  ..::..::|..:|.:        :..|.||.....:.:|.:|.:..|...  :
  Fly   397 SFMEDITAPELVDDYVDGIACWYESDK--------QSKKCESGGSDAAMELSVVRNEIKTFTELV 453

  Fly   513 HLAFMQIF 520
            ...|::::
  Fly   454 EKKFVKVY 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4950	NP_648855.2	LRR	96..411	CDD:443914	88/319 (28%)
		leucine-rich repeat	96..119	CDD:275380	5/22 (23%)
		leucine-rich repeat	120..143	CDD:275380	10/22 (45%)
		leucine-rich repeat	144..167	CDD:275380	0/22 (0%)
		leucine-rich repeat	168..191	CDD:275380	8/22 (36%)
		leucine-rich repeat	192..215	CDD:275380	7/22 (32%)
		leucine-rich repeat	216..239	CDD:275380	6/22 (27%)
		leucine-rich repeat	240..299	CDD:275380	16/63 (25%)
		leucine-rich repeat	300..321	CDD:275380	6/20 (30%)
		leucine-rich repeat	322..345	CDD:275380	7/22 (32%)
		leucine-rich repeat	346..365	CDD:275380	9/18 (50%)
		leucine-rich repeat	370..394	CDD:275380	7/23 (30%)
		leucine-rich repeat	395..420	CDD:275380	0/24 (0%)
alrm	NP_651393.1	leucine-rich repeat	91..114	CDD:275380	5/22 (23%)
		LRR	<100..426	CDD:443914	97/388 (25%)
		leucine-rich repeat	115..138	CDD:275380	10/46 (22%)
		leucine-rich repeat	139..162	CDD:275380	8/22 (36%)
		leucine-rich repeat	163..186	CDD:275380	7/22 (32%)
		leucine-rich repeat	187..210	CDD:275380	6/22 (27%)
		leucine-rich repeat	211..283	CDD:275380	20/73 (27%)
		leucine-rich repeat	284..319	CDD:275380	9/34 (26%)
		leucine-rich repeat	320..343	CDD:275380	12/22 (55%)
		leucine-rich repeat	344..365	CDD:275380	7/47 (15%)