Protein Alignment CG4950 and 2mit

DIOPT Version :10

• Sequence 1: NP_648855.2
• Gene: CG4950 / 39783
• FlyBaseID: FBgn0036587
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001262529.1
• Gene: 2mit / 41616
• FlyBaseID: FBgn0260793
• Length: 1155
• Species: Drosophila melanogaster
• Alignment Length: 413
• Identity: 101/413 - (24%)
• Similarity: 169/413 - (40%)
• Gaps: 100/413 - (24%)

  Fly   108 ELTRNAFSAASNLTYLNLAYNNLTSIQTSVFIGANVLMRLDLSYNEISSLSVNAFCGLHTISQIY 172
            ||..||.:...|||:.:|...|.|..|...  ...|:..:|||.|::.|||::.|   :.:.|:.
  Fly    89 ELELNAPANKLNLTHRDLRTFNSTGGQWKG--DFQVITAMDLSSNQLESLSLDNF---NQLRQLD 148

  Fly   173 LTGNLLKELHNDIFKDNEYLEKVSFE--GNLLTSIQPEVF-RNMRRIKEVNLSNNRLIFIHPDTF 234
            |..|.|:.:...:...|..|..|:.:  .|..:.|....| :.:.::|.:||::|.|:.|..::|
  Fly   149 LGNNSLEVIPLSLADTNMSLPFVTLDLSCNKFSQISTSFFAQRLPQLKNLNLAHNELLNISRESF 213

  Fly   235 ADAASLENLVLSYNELKNFQLTEKNIVHQLHLDNNYLTNLTINATRFVRASHNQISELFLHQSLH 299
            .:...|:.||||:|.:.               |.:|.|.|.:...:::..|||::|.
  Fly   214 YNLLELQTLVLSHNNIS---------------DIDYETFLALPNLQYLDLSHNRLSG-------- 255

  Fly   300 IETLDLSANKLSSISNITNITHMLYLDVSDNPIGPLNISTFSQLKRLRGLNLRGTG--------- 355
                       |:|..:..|..::.|.::.||...:.:..|.....|:.|:..|||
  Fly   256 -----------SAIRALQGIPDLVSLSIAYNPDVGVAMQEFVASWSLKELDASGTGLCQVPAALA 309

  Fly   356 --IRELKF----------GMFSKQKYLEELDLSFNNLTILNLDMFVPYLTNLKKFLIDGNGLTE- 407
              :|.||.          |.......|:.||||.:.:..:. |..:..|..|:...:|.|.|..
  Fly   310 QSVRTLKLSDNWLKAINCGDMDSYPLLQYLDLSHSRIAQVE-DDALGRLELLESLFLDRNLLMRV 373

  Fly   408 ------------LQGNRTFSEAFPQ-------LQKLGVSRNRFNCSYLHHLLIPP-SLPESVVLN 452
                        ||.|: ..|..||       ||.|.:|.||.       :.:|| |||:.:.||
  Fly   374 PSSLPPSLEHLFLQHNQ-IMELPPQAFVGLVNLQTLDLSNNRL-------IFLPPLSLPKLLTLN 430

  Fly   453 IE-------PDTNLDETPHIRDV 468
            :|       ..:.:...|.:||:
  Fly   431 LESSGVESVSQSIVHTLPQLRDL 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4950	NP_648855.2	LRR	96..411	CDD:443914	80/339 (24%)
		leucine-rich repeat	96..119	CDD:275380	4/10 (40%)
		leucine-rich repeat	120..143	CDD:275380	6/22 (27%)
		leucine-rich repeat	144..167	CDD:275380	8/22 (36%)
		leucine-rich repeat	168..191	CDD:275380	5/22 (23%)
		leucine-rich repeat	192..215	CDD:275380	5/25 (20%)
		leucine-rich repeat	216..239	CDD:275380	7/22 (32%)
		leucine-rich repeat	240..299	CDD:275380	14/58 (24%)
		leucine-rich repeat	300..321	CDD:275380	3/20 (15%)
		leucine-rich repeat	322..345	CDD:275380	4/22 (18%)
		leucine-rich repeat	346..365	CDD:275380	9/39 (23%)
		leucine-rich repeat	370..394	CDD:275380	7/23 (30%)
		leucine-rich repeat	395..420	CDD:275380	8/37 (22%)
2mit	NP_001262529.1	LRR	<106..458	CDD:443914	94/396 (24%)
		leucine-rich repeat	124..143	CDD:275380	8/21 (38%)
		leucine-rich repeat	144..167	CDD:275380	5/22 (23%)
		leucine-rich repeat	172..194	CDD:275380	3/21 (14%)
		leucine-rich repeat	195..218	CDD:275380	7/22 (32%)
		leucine-rich repeat	219..242	CDD:275380	10/37 (27%)
		leucine-rich repeat	243..311	CDD:275380	16/86 (19%)
		leucine-rich repeat	312..335	CDD:275380	4/22 (18%)
		leucine-rich repeat	336..359	CDD:275380	7/23 (30%)
		leucine-rich repeat	360..380	CDD:275380	4/19 (21%)
		leucine-rich repeat	381..404	CDD:275380	6/23 (26%)
		leucine-rich repeat	405..449	CDD:275380	14/50 (28%)