DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4950 and CG4781

DIOPT Version :9

Sequence 1:NP_001261934.1 Gene:CG4950 / 39783 FlyBaseID:FBgn0036587 Length:574 Species:Drosophila melanogaster
Sequence 2:NP_611951.1 Gene:CG4781 / 37943 FlyBaseID:FBgn0035043 Length:469 Species:Drosophila melanogaster


Alignment Length:322 Identity:87/322 - (27%)
Similarity:129/322 - (40%) Gaps:73/322 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   288 QISELFLHQSLHIETLDLSANKLSSISNITNITHMLYLDVSDNPIGPLNISTFSQLKRLRGLNLR 352
            ::::|.|...|:|::||||.|.|.|:...|: ..:..|::..|.|..|....|.||..||.|.|.
  Fly    76 KVADLSLLLPLYIDSLDLSWNALDSVPIFTS-DSLHQLNLRHNNISQLVSGNFKQLTSLRELYLG 139

  Fly   353 GTGIRELKFGMFSKQKYLEELDLSFNNLTILNLDMFVPYLTNLKKFLIDGNGLTELQGNRTFSEA 417
            ...|.:|:.|.|....:|:.|||:.|||.:|...:|.|.|.         .|..::..||.|:|:
  Fly   140 WNSIGKLESGSFDGLPHLQVLDLAHNNLHLLPGHLFAPLLV---------LGTLDISWNRRFNES 195

  Fly   418 FPQLQK-LGV----SRNRFNCSYLHHL-------------------LIPPSLPESVVLNIEPDTN 458
            ...|.. |||    |..|.:...|:.|                   .||..|||: :|.::...|
  Fly   196 GGDLYTGLGVNWKLSTLRLDACSLNDLHLPVNAPLKELSLRRNQLKRIPTQLPET-LLRLDISDN 259

  Fly   459 LDETPHIRDVSCISQ-----------SQEVVNASFTAEESKLESQIQMLSKQLD---------IV 503
            |.|.....|.:.::|           .|.||..|.| ....||:.....|:||.         |:
  Fly   260 LLEELLPEDTANLTQVRQLFIEDMPVLQRVVANSLT-HVDVLETLSFQNSRQLSHLDAEAFGPIM 323

  Fly   504 GSHSK-----------------NLELHLAFMQIFAYVMGGLVLVGVVSLITLRYLKNQRSGR 548
            .:.:|                 |..|...|.|:....:.||.|.....|:.|:.|..|.:||
  Fly   324 TTPTKKRALRSLSFRGTMLRTFNSTLAPIFTQLAELDLNGLPLQCDCELVWLKQLPVQTNGR 385

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4950NP_001261934.1 leucine-rich repeat 96..119 CDD:275380
LRR_8 118..178 CDD:290566
leucine-rich repeat 120..143 CDD:275380
leucine-rich repeat 144..167 CDD:275380
leucine-rich repeat 168..191 CDD:275380
LRR_8 192..250 CDD:290566
leucine-rich repeat 192..215 CDD:275380
LRR_RI <207..432 CDD:238064 49/148 (33%)
leucine-rich repeat 216..239 CDD:275380
leucine-rich repeat 240..299 CDD:275380 2/10 (20%)
LRR_8 299..356 CDD:290566 20/56 (36%)
leucine-rich repeat 300..321 CDD:275380 9/20 (45%)
leucine-rich repeat 322..345 CDD:275380 7/22 (32%)
LRR_8 344..405 CDD:290566 19/60 (32%)
leucine-rich repeat 346..365 CDD:275380 7/18 (39%)
leucine-rich repeat 370..394 CDD:275380 11/23 (48%)
leucine-rich repeat 395..420 CDD:275380 5/24 (21%)
CG4781NP_611951.1 leucine-rich repeat 90..108 CDD:275380 8/18 (44%)
LRR_8 108..167 CDD:290566 20/58 (34%)
leucine-rich repeat 109..132 CDD:275380 7/22 (32%)
LRR_RI <121..>261 CDD:238064 43/149 (29%)
leucine-rich repeat 133..156 CDD:275380 8/22 (36%)
leucine-rich repeat 157..180 CDD:275380 10/22 (45%)
leucine-rich repeat 181..208 CDD:275380 9/26 (35%)
leucine-rich repeat 230..253 CDD:275380 5/23 (22%)
leucine-rich repeat 254..274 CDD:275380 4/19 (21%)
leucine-rich repeat 275..299 CDD:275380 5/24 (21%)
leucine-rich repeat 300..319 CDD:275380 5/18 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR45617
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.100

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