Protein Alignment CG4950 and Gp150

DIOPT Version :10

• Sequence 1: NP_648855.2
• Gene: CG4950 / 39783
• FlyBaseID: FBgn0036587
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_477049.2
• Gene: Gp150 / 37549
• FlyBaseID: FBgn0013272
• Length: 1076
• Species: Drosophila melanogaster
• Alignment Length: 501
• Identity: 126/501 - (25%)
• Similarity: 215/501 - (42%)
• Gaps: 57/501 - (11%)

  Fly    45 EAFCTVTGFTVTHSQNVVIKNIPPGNMVKFMKFYESTLLYMPFHLFETFPYL------KTLDVSN 103
            |||..:......:..:|.:..|.|...|...|....|:......:..:..||      :.||.|.
  Fly   335 EAFHGLNELYAVNLTDVGLAIINPDTFVGNKKLRMLTISGNDLSVMSSIHYLLKSSSIEELDFSR 399

  Fly   104 TNILELTRNAFSAASNLTYLNLAYNNLTSIQTSVFIGANVLMRLDLSYNEISSLSVNAFCGLHTI 168
            .|::||...|||..||:.|:||:.|:|..:....|....:|..||||||.::.|..:.|.|. |:
  Fly   400 NNLMELNPKAFSHLSNVVYINLSQNSLKKLPEKAFEKVTLLEELDLSYNSLTELPRDIFNGT-TL 463

  Fly   169 SQIYLTGNLLKELHNDIFKDNEYLEKVSFEGNLLTSIQPEVFRNMRRIKEVNLSNNRLIFIHPDT 233
            |.::|..|   ..:.|:....:.|:::....|.:..:...:|..|..:..:||..|.:..|.||:
  Fly   464 SILHLKYN---TFNGDLHFGTKDLQQLDLSFNSIVQVHHSMFDKMPGLTNLNLKGNGIKKIQPDS 525

  Fly   234 FADAASLENLVLSYNELKN------FQLTEKNIVH--------QLHLDN--NYLTNLTINATRFV 282
            |....:|.::.||.|:|..      |:.:|.:::.        ||..|.  :|....|:   .::
  Fly   526 FLTLKNLRHIDLSINDLDQISGMLFFKNSELDVIRLNDNPRLSQLPTDGFLSYSGEFTV---YYL 587

  Fly   283 RASHNQISELFLHQSL----HIETLDLSANKLSSISN--ITNITHMLYLDVSDNPIGPLNISTFS 341
            ..|:..|..|. |::.    |:.||.|:.|.::.:..  .|.:..::.||:|:|.|..::...|.
  Fly   588 DISNCAIGPLG-HKAFSTMPHLTTLKLAWNNINHLPREIFTGLHKLIDLDLSNNLITRMDDLIFM 651

  Fly   342 QLKRLRGLNLRGTGIRELKFGMFSKQKYLEELDLSFNNLTIL--NLDMFVPY--LTNLKKFLIDG 402
            ....|..|:|.|..|..|...:|.....|..||::...||.|  :.|:...|  ..:|:.|...|
  Fly   652 DNGELTKLSLAGNPISRLSVRLFLPLHQLRCLDVNDCELTTLLSDRDLGAGYKIFDSLRSFNASG 716

  Fly   403 NGLTELQGNRTFSEAFPQLQKLGVSRNRFNC--------SY--LHHLLIPPSLPESVVLNIEPDT 457
            |.:.::.....  ::|..|:.|.::.|...|        ||  |...:.|..||  |:.|:|.|.
  Fly   717 NLIKKISSEDV--KSFKNLRSLDITNNPLKCTPDFQEFISYVTLQMQMTPKRLP--VLANLEDDA 777

  Fly   458 NLDETPHIRDVSCISQSQEV---VNASFTAEESKLESQIQMLSKQL 500
            .:.:...:......|.:.||   ...|...:|.|.:|....|.|:|
  Fly   778 TIVQLETLAQAGWSSLAHEVCKHAEGSDLLDEKKADSAEAKLEKRL 823

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4950	NP_648855.2	LRR	96..411	CDD:443914	91/346 (26%)
		leucine-rich repeat	96..119	CDD:275380	10/28 (36%)
		leucine-rich repeat	120..143	CDD:275380	6/22 (27%)
		leucine-rich repeat	144..167	CDD:275380	10/22 (45%)
		leucine-rich repeat	168..191	CDD:275380	4/22 (18%)
		leucine-rich repeat	192..215	CDD:275380	4/22 (18%)
		leucine-rich repeat	216..239	CDD:275380	7/22 (32%)
		leucine-rich repeat	240..299	CDD:275380	16/78 (21%)
		leucine-rich repeat	300..321	CDD:275380	5/22 (23%)
		leucine-rich repeat	322..345	CDD:275380	6/22 (27%)
		leucine-rich repeat	346..365	CDD:275380	6/18 (33%)
		leucine-rich repeat	370..394	CDD:275380	8/27 (30%)
		leucine-rich repeat	395..420	CDD:275380	5/24 (21%)
Gp150	NP_477049.2	LRR	341..758	CDD:443914	105/426 (25%)
		leucine-rich repeat	343..366	CDD:275380	4/22 (18%)
		leucine-rich repeat	367..391	CDD:275380	3/23 (13%)
		leucine-rich repeat	393..415	CDD:275380	9/21 (43%)
		leucine-rich repeat	416..439	CDD:275380	6/22 (27%)
		leucine-rich repeat	440..483	CDD:275380	15/46 (33%)
		leucine-rich repeat	463..481	CDD:275380	4/20 (20%)
		leucine-rich repeat	484..507	CDD:275380	4/22 (18%)
		leucine-rich repeat	508..531	CDD:275380	7/22 (32%)
		leucine-rich repeat	532..569	CDD:275380	7/36 (19%)
		leucine-rich repeat	556..583	CDD:275380	4/26 (15%)
		leucine-rich repeat	570..607	CDD:275380	8/40 (20%)
		leucine-rich repeat	608..631	CDD:275380	5/22 (23%)
		leucine-rich repeat	632..655	CDD:275380	6/22 (27%)
		leucine-rich repeat	656..674	CDD:275380	6/17 (35%)
		leucine-rich repeat	733..745	CDD:275378	3/11 (27%)