Protein Alignment CG4950 and CG4168

DIOPT Version :10

• Sequence 1: NP_648855.2
• Gene: CG4950 / 39783
• FlyBaseID: FBgn0036587
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_609740.4
• Gene: CG4168 / 34889
• FlyBaseID: FBgn0028888
• Length: 1330
• Species: Drosophila melanogaster
• Alignment Length: 594
• Identity: 139/594 - (23%)
• Similarity: 252/594 - (42%)
• Gaps: 128/594 - (21%)

  Fly    15 ILAISSCDGSGGDIPLRCDEYDSM------GYMDVNEAFCTVTGFTVTHSQNVVIKNIPPGNMVK 73
            |.|:.|...:...|.||.::...:      |...:.|...:....|:.|.  :|.:|:.     :
  Fly   501 IFAVDSWGSNLQTILLRNNKITHLHLGSFAGLEQIQEISLSFNDITIHHP--LVFENVS-----R 558

  Fly    74 FMKFYESTLLYMPFHLFETFPYLKT---------LDVSNTNILELTRNAFSAASNLTYLNLAYNN 129
            .:|..|.:....|....|:...|..         |.:.|.|:.:::..:|:....|:|:||::|.
  Fly   559 TLKILELSFAVFPARSLESLDPLDALLPLSQLIWLGLDNNNLKQVSNESFAQMRELSYINLSFNQ 623

  Fly   130 LTSIQTSVF--IGANVLMRLDLSYNEISSLSVNAFCGLHTISQIYLTGNLLKELHNDIFKDNEYL 192
            |.::...:|  ...:.|:.:|||||.:..|....|..|..:..:.|..|.|:.:....|.:.|:|
  Fly   624 LKTLPRGLFQSDAHSHLVEIDLSYNGLERLEAQTFHSLGDLQTLNLQSNRLRTIARHAFHNLEFL 688

  Fly   193 EKVSFEGNLLTSIQPEVFRNMRRIKEVNLSNNRLIFIHPDTF---ADAASLENLVLSYNELKNF- 253
            ..:....|.|.:|....|..:..:..::|.:|:|..:...:|   ::..:...|.:|:|.:.:|
  Fly   689 RYLDLSYNRLVNISHGAFTVLPNLAALDLMHNQLCSLSLKSFLYVSNTTTPLRLNVSHNHIASFY 753

  Fly   254 -QLTEKNIVHQLHLDNNYL------TNLTINATRFVRASHNQISELFLH---QSLHIETLDLSAN 308
             :|:....::||.:.:|::      |||. |..||:..:|||:..|..|   ....:|.|:::.|
  Fly   754 DELSSYMYIYQLDISHNHVTKSDSFTNLA-NTLRFLNLAHNQLGSLQSHAFGDLEFLEILNVAHN 817

  Fly   309 KLSSI--SNITNITHMLYLDVSDNPIGPLNISTFSQLKRLRGLNLRGTGIRELKFGMFSKQKYLE 371
            .|:|:  .:...:..:..||:|.|.:..|.:..||.|::||.|.:....:|.|...:|...: ||
  Fly   818 NLTSLRRRSFQGLNSLQELDLSHNQLDQLQVEQFSNLRKLRILRINSNRLRALPREVFMNTR-LE 881

  Fly   372 ELD-------------------------LSFNNLTILNLDMFVPYLTNLKKFLID----GNGLTE 407
            .||                         :|.|||..|:..||:.     .:||.|    .|.:|.
  Fly   882 FLDIAENQLSVWPVPAFTDIGFTLRSIQMSHNNLEYLDASMFIN-----SQFLYDISLARNRITI 941

  Fly   408 LQGNRTFS---------------------EAF---PQLQKLGVSRNRFNCSYLHHL---LIPP-S 444
            |..| |||                     |.|   |:|:||.          |||:   ::|| .
  Fly   942 LPDN-TFSFLNNLTNLDLSQNPLVTTNLREVFVHTPRLRKLS----------LHHMGLYVLPPLK 995

  Fly   445 LPESVVLNIEPDTNLDETP-----HIRDVSCISQSQEVVNASFTAEESKLESQIQMLSKQLDIVG 504
            ||....|::..:...:.:|     |:|.|: :|.: ::.|||..||.  |...:::    ||:..
  Fly   996 LPLLSYLDVSGNYLQELSPLGSLRHLRHVN-VSHN-KLTNASCAAEH--LPPSVRV----LDLAH 1052

  Fly   505 SHSKNLELH 513
            :..:.:.||
  Fly  1053 NPLRRITLH 1061

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4950	NP_648855.2	LRR	96..411	CDD:443914	90/370 (24%)
		leucine-rich repeat	96..119	CDD:275380	5/31 (16%)
		leucine-rich repeat	120..143	CDD:275380	7/24 (29%)
		leucine-rich repeat	144..167	CDD:275380	9/22 (41%)
		leucine-rich repeat	168..191	CDD:275380	4/22 (18%)
		leucine-rich repeat	192..215	CDD:275380	5/22 (23%)
		leucine-rich repeat	216..239	CDD:275380	4/25 (16%)
		leucine-rich repeat	240..299	CDD:275380	19/69 (28%)
		leucine-rich repeat	300..321	CDD:275380	5/22 (23%)
		leucine-rich repeat	322..345	CDD:275380	8/22 (36%)
		leucine-rich repeat	346..365	CDD:275380	5/18 (28%)
		leucine-rich repeat	370..394	CDD:275380	11/48 (23%)
		leucine-rich repeat	395..420	CDD:275380	12/52 (23%)
CG4168	NP_609740.4	PRK15370	<69..>353	CDD:185268
		leucine-rich repeat	99..118	CDD:275380
		leucine-rich repeat	122..146	CDD:275380
		leucine-rich repeat	147..170	CDD:275380
		leucine-rich repeat	171..194	CDD:275380
		leucine-rich repeat	195..214	CDD:275380
		leucine-rich repeat	215..236	CDD:275380
		leucine-rich repeat	266..287	CDD:275380
		leucine-rich repeat	288..311	CDD:275380
		leucine-rich repeat	312..338	CDD:275380
		LRR	<338..651	CDD:443914	34/156 (22%)
		leucine-rich repeat	339..365	CDD:275380
		leucine-rich repeat	366..388	CDD:275380
		leucine-rich repeat	389..412	CDD:275380
		leucine-rich repeat	414..436	CDD:275380
		leucine-rich repeat	437..459	CDD:275380
		leucine-rich repeat	460..483	CDD:275380
		leucine-rich repeat	484..510	CDD:275380	3/8 (38%)
		leucine-rich repeat	511..534	CDD:275380	4/22 (18%)
		leucine-rich repeat	535..589	CDD:275380	10/60 (17%)
		LRR	543..971	CDD:443914	102/442 (23%)
		leucine-rich repeat	590..613	CDD:275380	4/22 (18%)
		leucine-rich repeat	614..639	CDD:275380	7/24 (29%)
		leucine-rich repeat	640..663	CDD:275380	9/22 (41%)
		leucine-rich repeat	664..687	CDD:275380	4/22 (18%)
		leucine-rich repeat	688..711	CDD:275380	5/22 (23%)
		leucine-rich repeat	712..735	CDD:275380	4/22 (18%)
		leucine-rich repeat	740..783	CDD:275380	11/43 (26%)
		leucine-rich repeat	785..808	CDD:275380	7/22 (32%)
		leucine-rich repeat	809..832	CDD:275380	5/22 (23%)
		leucine-rich repeat	833..856	CDD:275380	8/22 (36%)
		leucine-rich repeat	857..879	CDD:275380	6/21 (29%)
		leucine-rich repeat	880..900	CDD:275380	4/19 (21%)
		leucine-rich repeat	905..928	CDD:275380	7/27 (26%)
		LRR	911..>1203	CDD:443914	46/175 (26%)
		leucine-rich repeat	929..952	CDD:275380	9/23 (39%)
		leucine-rich repeat	953..977	CDD:275380	2/23 (9%)
		leucine-rich repeat	978..1020	CDD:275380	12/51 (24%)
		leucine-rich repeat	1045..1068	CDD:275380	4/21 (19%)
		leucine-rich repeat	1069..1090	CDD:275380
		leucine-rich repeat	1091..1114	CDD:275380
		leucine-rich repeat	1115..1161	CDD:275380
		leucine-rich repeat	1162..1190	CDD:275380
		PCC	1230..>1298	CDD:188093