DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4950 and CG42346

DIOPT Version :9

Sequence 1:NP_001261934.1 Gene:CG4950 / 39783 FlyBaseID:FBgn0036587 Length:574 Species:Drosophila melanogaster
Sequence 2:NP_001036303.2 Gene:CG42346 / 3355160 FlyBaseID:FBgn0259677 Length:1817 Species:Drosophila melanogaster


Alignment Length:579 Identity:130/579 - (22%)
Similarity:233/579 - (40%) Gaps:115/579 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    57 HSQNVVIKNIPPGNMVKFMKFYESTLLYMPFHLFETFPYLKTLDVSNTNILELTRNAFSAASNLT 121
            |:...|..|:|   .::.:...|:.:|.:|...|.....:..:.:.:..|..:..|.||...||.
  Fly   545 HTIGGVFSNLP---QLREVFLSENNILELPADAFTNSTNVDVIYLESNAIAHIDPNVFSTLVNLD 606

  Fly   122 YLNLAYNNLTSIQTSVFIGANVLMRLDLSYNEISSLSVNAFCGLHTISQIYLTGNLLKELHNDIF 186
            :|.|..|.:..:..::|..:..|..|.|..|||..|.:..|..|..:.::.|..|.::.:...:|
  Fly   607 HLYLRSNFIPLLPVTLFDKSTKLTSLSLDNNEIQDLEIGMFRKLEHLREVRLHNNRIRRVRRGVF 671

  Fly   187 KDNEYLEKVSFEGNLLTSIQPEVFRNMRRIKEVNLSNNRLIFIHPDTFADAASLENLVLSYNELK 251
            :....|:::..:.|.:..|:|:.|..:..::.:||.:|:|..:. |.|.|    ||     :.|.
  Fly   672 EPLPSLQELHIQKNSIEDIEPQAFHTLENMQHINLQDNQLTVLE-DIFPD----EN-----SSLL 726

  Fly   252 NFQLTEKNIVHQLH--------------LDNNYLTNLTINATRFVRASHNQISELFLHQSLHIET 302
            :.|| |.|.:|::|              |.:|.||               ::...|...:..:..
  Fly   727 SVQL-EANYLHKVHPRTFSRQQKVQIMWLKDNQLT---------------RVERSFFADTPQLGR 775

  Fly   303 LDLSANKLSSISNIT--NITHMLYLDVSDNPIGPLNISTFSQLKRLRGLNLRGTGIRELKFGMFS 365
            |.||.||:..|...|  |:..:.:||:|.|.:..|....|:.|:.|..|:|....|..::...|:
  Fly   776 LYLSDNKIRDIEKDTFVNLLLLQFLDLSGNQLRQLRRDYFAPLQDLEELSLARNHIEAIEGYAFA 840

  Fly   366 KQKYLEELDLSFNNLTILNLDMF-----------------------VPYLTNLKKFLIDGNGL-- 405
            |.|.|:.||||.|.|..|..|:|                       ...||||.:..::.|.|  
  Fly   841 KLKNLKSLDLSHNPLVQLTRDIFSNEFPLNSLNLGNCSLRKLEQHAFKSLTNLNELNLERNQLNP 905

  Fly   406 TELQGNRTFSEAFPQLQKLGVSRNRFNCSYLHHLLIPPSLPESVVLNIEPDTNLDETPHIRDVSC 470
            .::|     :...|.|::|.:|.|.|  ||...:.|...:             ||....::.:|.
  Fly   906 ADIQ-----TLDIPNLRRLLLSHNNF--SYAGSVGIMAGM-------------LDRLRSLQQLSM 950

  Fly   471 ISQSQEVVNASFTAEESKL------ESQIQMLSKQLDIVGSHSKNLELHLAFMQIFAYVMGGLVL 529
            .:.|...:.....|:.:.|      ::::..:::.:....:..|.|.|....:..|.::    .|
  Fly   951 SNCSLGQIPDLLFAKNTNLVRLDLCDNRLTQINRNIFSGLNVFKELRLCRNELSDFPHI----AL 1011

  Fly   530 VGVVSLITLRYLKNQ--------RSGRYDRSSIVFRSNATM------EANLT-LGSEDL 573
            ..:.:|.:|...:||        .||..:...::.|.|...      ..||| |.|.||
  Fly  1012 YNLSTLESLDLARNQLASIDFFKLSGTLNLRQLILRDNKITALSGFNAVNLTQLDSVDL 1070

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4950NP_001261934.1 leucine-rich repeat 96..119 CDD:275380 4/22 (18%)
LRR_8 118..178 CDD:290566 17/59 (29%)
leucine-rich repeat 120..143 CDD:275380 5/22 (23%)
leucine-rich repeat 144..167 CDD:275380 9/22 (41%)
leucine-rich repeat 168..191 CDD:275380 3/22 (14%)
LRR_8 192..250 CDD:290566 14/57 (25%)
leucine-rich repeat 192..215 CDD:275380 5/22 (23%)
LRR_RI <207..432 CDD:238064 67/265 (25%)
leucine-rich repeat 216..239 CDD:275380 7/22 (32%)
leucine-rich repeat 240..299 CDD:275380 14/72 (19%)
LRR_8 299..356 CDD:290566 18/58 (31%)
leucine-rich repeat 300..321 CDD:275380 8/22 (36%)
leucine-rich repeat 322..345 CDD:275380 7/22 (32%)
LRR_8 344..405 CDD:290566 22/83 (27%)
leucine-rich repeat 346..365 CDD:275380 4/18 (22%)
leucine-rich repeat 370..394 CDD:275380 11/46 (24%)
leucine-rich repeat 395..420 CDD:275380 4/26 (15%)
CG42346NP_001036303.2 leucine-rich repeat 303..325 CDD:275380
LRR_8 325..384 CDD:290566
leucine-rich repeat 327..350 CDD:275380
leucine-rich repeat 351..461 CDD:275380
LRR_8 373..433 CDD:290566
LRR_RI 397..648 CDD:238064 25/105 (24%)
leucine-rich repeat 399..422 CDD:275380
leucine-rich repeat 462..485 CDD:275380
LRR_8 465..520 CDD:290566
leucine-rich repeat 486..509 CDD:275380
LRR_8 508..567 CDD:290566 5/24 (21%)
leucine-rich repeat 510..533 CDD:275380
LRR_RI 527..785 CDD:238064 61/268 (23%)
leucine-rich repeat 534..556 CDD:275380 4/13 (31%)
LRR_8 555..613 CDD:290566 13/60 (22%)
leucine-rich repeat 557..580 CDD:275380 4/22 (18%)
leucine-rich repeat 581..604 CDD:275380 4/22 (18%)
LRR_8 604..663 CDD:290566 17/58 (29%)
leucine-rich repeat 605..628 CDD:275380 5/22 (23%)
leucine-rich repeat 629..652 CDD:275380 9/22 (41%)
LRR_8 652..711 CDD:290566 11/58 (19%)
leucine-rich repeat 653..676 CDD:275380 3/22 (14%)
leucine-rich repeat 677..700 CDD:275380 5/22 (23%)
leucine-rich repeat 701..748 CDD:275380 16/57 (28%)
leucine-rich repeat 725..736 CDD:275378 5/11 (45%)
leucine-rich repeat 749..772 CDD:275380 5/37 (14%)
LRR_8 771..831 CDD:290566 18/59 (31%)
leucine-rich repeat 773..793 CDD:275380 7/19 (37%)
LRR_RI 804..1076 CDD:238064 63/291 (22%)
LRR_8 821..903 CDD:290566 22/81 (27%)
leucine-rich repeat 821..844 CDD:275380 6/22 (27%)
leucine-rich repeat 845..868 CDD:275380 10/22 (45%)
leucine-rich repeat 869..892 CDD:275380 1/22 (5%)
leucine-rich repeat 893..915 CDD:275380 4/26 (15%)
leucine-rich repeat 916..944 CDD:275380 10/42 (24%)
leucine-rich repeat 945..968 CDD:275380 3/22 (14%)
LRR_8 967..1027 CDD:290566 9/63 (14%)
leucine-rich repeat 969..992 CDD:275380 1/22 (5%)
leucine-rich repeat 993..1014 CDD:275380 5/24 (21%)
LRR_8 1015..1075 CDD:290566 15/56 (27%)
leucine-rich repeat 1017..1040 CDD:275380 6/22 (27%)
leucine-rich repeat 1041..1064 CDD:275380 4/22 (18%)
LRR_RI <1047..1244 CDD:238064 9/24 (38%)
LRR_8 1063..1125 CDD:290566 5/8 (63%)
leucine-rich repeat 1089..1114 CDD:275380
leucine-rich repeat 1115..1162 CDD:275380
LRR_8 1163..1219 CDD:290566
leucine-rich repeat 1163..1186 CDD:275380
leucine-rich repeat 1187..1210 CDD:275380
leucine-rich repeat 1211..1233 CDD:275380
leucine-rich repeat 1234..1257 CDD:275380
LRR_8 1235..1292 CDD:290566
leucine-rich repeat 1258..1279 CDD:275380
leucine-rich repeat 1282..1306 CDD:275380
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45453705
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR45617
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
32.940

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