Protein Alignment l(3)72Dr and GGH

DIOPT Version :9

• Sequence 1: NP_730120.1
• Gene: l(3)72Dr / 39778
• FlyBaseID: FBgn0263608
• Length: 345
• Species: Drosophila melanogaster
• Sequence 2: NP_003869.1
• Gene: GGH / 8836
• HGNCID: 4248
• Length: 318
• Species: Homo sapiens
• Alignment Length: 314
• Identity: 96/314 - (30%)
• Similarity: 172/314 - (54%)
• Gaps: 31/314 - (9%)

  Fly    16 PTVGVMCIDIATQLQQNFSGAYHSYLAASYVKFLEASGAHVVPIWIGRERAYYALMMSQLNGILL 80
            |.:|::......::.:|: |.|  |:||||||:||::||.|||:.:......|.::...:||||.
Human    34 PIIGILMQKCRNKVMKNY-GRY--YIAASYVKYLESAGARVVPVRLDLTEKDYEILFKSINGILF 95

  Fly    81 PGGAVFIDEADRQANPDVTSDCVRSAELIYQLAMERNMRAKKLDDRGAYFPVWGTCLGF-QLILI 144
            |||:|.:..          ||..:.|::.|.|:::      ..|| |.||||||||||| :|.|:
Human    96 PGGSVDLRR----------SDYAKVAKIFYNLSIQ------SFDD-GDYFPVWGTCLGFEELSLL 143

  Fly   145 HAAEAPNVRIACQPMREAMPVTLTDDYQQSQLLGSLPKSVADEMEKHPFACHQHRYCIT-KESLE 208
            .:.|.  :..|...:..|||:..|.....|::..:.|..:...:...|...:.|::.:: |....
Human   144 ISGEC--LLTATDTVDVAMPLNFTGGQLHSRMFQNFPTELLLSLAVEPLTANFHKWSLSVKNFTM 206

  Fly   209 SYGLAKDWHPLATQKDTSGLEFITIVEHRRFPIFGCQFHPERAAFEQLFNSPDKCYMAHSRMGID 273
            :..|.|.::.|.|..| ..:|||:.:|..::|::|.|:|||:|.:|  :.:.|.  ::|:...:.
Human   207 NEKLKKFFNVLTTNTD-GKIEFISTMEGYKYPVYGVQWHPEKAPYE--WKNLDG--ISHAPNAVK 266

  Fly   274 LSQIFGSRFVDFCRRNNNQFESDKLKTRHLIWNWQPVFSGKFKGSNWQQCYLFE 327
            .:......||:..|:||:.|:|:..:.:.||:.:.|:::|..  |::||||:|:
Human   267 TAFYLAEFFVNEARKNNHHFKSESEEEKALIYQFSPIYTGNI--SSFQQCYIFD 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(3)72Dr	NP_730120.1	GATase1_Glutamyl_Hydrolase	23..313	CDD:153218	87/291 (30%)
GGH	NP_003869.1	GATase1_Glutamyl_Hydrolase	36..306	CDD:153218	88/296 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165155326
Domainoid	1	1.000	138	1.000	Domainoid score	I4852
eggNOG	1	0.900	-	-		E1_KOG1559
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7038
OMA	1	1.010	-	-		QHG54943
OrthoDB	1	1.010	-	-		D539287at33208
OrthoFinder	1	1.000	-	-		FOG0002965
OrthoInspector	1	1.000	-	-		otm40939
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11315
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5199
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	12	11.800