DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5027 and Pdia5

DIOPT Version :9

Sequence 1:NP_648847.3 Gene:CG5027 / 39775 FlyBaseID:FBgn0036579 Length:430 Species:Drosophila melanogaster
Sequence 2:NP_082571.1 Gene:Pdia5 / 72599 MGIID:1919849 Length:517 Species:Mus musculus


Alignment Length:231 Identity:58/231 - (25%)
Similarity:91/231 - (39%) Gaps:37/231 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    28 VLELSDRFID--VRHEGQWLVMFYAPWCGYCKKTEPIFALVAQALHATNVRVGRL---DCTKYPA 87
            |..|:|...|  |:.....||||:|||||:|||.:|.|...|:.||......|.|   |.|...|
Mouse   276 VYHLTDEDFDQFVKEHSSVLVMFHAPWCGHCKKMKPEFESAAEVLHGDAESSGVLAAVDATVNEA 340

  Fly    88 AAKEFKVRGYPTIMFIKGNMEFTYNGDRGRDELVDYALRMSGPP-------------VQLVTRTE 139
            .|..|.:..:||:.:.|...:......|.:.:.:::......||             :.||....
Mouse   341 LAGRFHISAFPTLKYFKNGEQQAVPALRTKKKFIEWMQNPEAPPPPEPTWEEQQTSVLHLVGDNF 405

  Fly   140 SVDMLKGSHTIFFIFVGQQEGVVW--------DTYYAAAEGYQEHGFFYATSED-IAAQHFDFEK 195
            ...:.|..||:...:      ..|        ..:.|.|:.::|.......:.| :..::.|..:
Mouse   406 RDTLKKKKHTLVMFY------APWCPHCKKVIPHFTATADAFKEDRKIACAAVDCVKDKNQDLCQ 464

  Fly   196 LPAVIVYKEEQHHFYPHGHLA--HEMDPNEVNETVF 229
            ..||..|  ...|:|.:|.|.  :|.|..|:..|.|
Mouse   465 QEAVKAY--PTFHYYHYGKLVEKYESDRTELGFTSF 498

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5027NP_648847.3 PDI_a_TMX3 27..128 CDD:239298 33/104 (32%)
ER_PDI_fam 28..>355 CDD:273457 58/231 (25%)
Pdia5NP_082571.1 PDI_b_PDIR_N 26..137 CDD:239365
PTZ00102 122..517 CDD:240266 58/231 (25%)
PDI_a_PDIR 150..254 CDD:239295
PDI_a_PDIR 275..377 CDD:239295 33/100 (33%)
PDI_a_PDIR 396..499 CDD:239295 23/111 (21%)
Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138 514..517
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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