DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5027 and zgc:136472

DIOPT Version :9

Sequence 1:	NP_648847.3	Gene:	CG5027 / 39775	FlyBaseID:	FBgn0036579	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_001035331.1	Gene:	zgc:136472 / 678514	ZFINID:	ZDB-GENE-060421-2552	Length:	510	Species:	Danio rerio

Alignment Length:	378	Identity:	72/378 - (19%)
Similarity:	137/378 - (36%)	Gaps:	99/378 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LISALLL--TLGSTGLSSKVLELSDRFIDVR---------HEGQWLVMFYAPWCGYCKKTEPIFA 64
            ||..|.|  ||..: .|:.::|..|..:..:         || |.||.||||..|....:...|.
Zfish     9 LIVCLFLHQTLAES-QSNSIVEDKDVLVLTKSNFHRALKQHE-QLLVHFYAPLSGQSLGSILEFR 71

  Fly    65 LVAQALHA--TNVRVGRLDCTKYPAAAKEFKVRGYPTIMFIKGNMEFTYNGDRGRD--------- 118
            ..|.||..  ::|::|.:|..|....|:...:...|:|       ....:||:...
Zfish    72 EAAGALKEADSDVKLGGVDVKKEKELAESLNITTLPSI-------RLYLSGDKNNPVYCPVLKSS 129

  Fly   119 -ELVDYALRMSGPPVQLVTRTESVD--MLKGSHTIFFIFVGQQEGVVWDTYYAAAEGYQEHGFFY 180
             .::.:..|.:||...:::....::  :.:....:..:|...:||.|              ..||
Zfish   130 ASILTWLKRRAGPSADIISNVTQLENFLRRDELVVLALFKDLEEGAV--------------KVFY 180

  Fly   181 ATSEDIA------AQH------FDFEKLPAVIVYKEEQHHFYPHGHLAHEMDPNEVNETVFQWVN 233
            .|:.|:|      .:|      |:..:...:::.|.:....:       ||:.:.|...:..::.
Zfish   181 ETAADVADLPFGVTRHHEVFSKFEISRDSVLLIRKSKLDQQF-------EMESSTVKTDLVHFIR 238

  Fly   234 VERFTLFPKVTRFNIHQLLKTNKYLVLAVVQEDKLNQ-IATHELEFRDMVEGVIRK-HRA----- 291
            :....|   ||.:|             .|.....||. |..|.|.|....||...: :.|
Zfish   239 LYEMEL---VTEYN-------------GVTASKILNSVILNHLLLFISKTEGGFEEIYNAYETTA 287

  Fly   292 -RYHDKFQFGWIGEPSIAHSIIL-------DQLPTPHLIAINSSTQHHFIPED 336
             |:..|..|..|....:.:..::       ::.|...::.::::.|:. :|.|
Zfish   288 ERFRGKVLFVLIDVSELRNGRMMEYFHVRSEEAPQVRMVNLSNNLQYQ-LPSD 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5027	NP_648847.3	PDI_a_TMX3	27..128	CDD:239298	26/121 (21%)
CG5027	NP_648847.3	ER_PDI_fam	28..>355	CDD:273457	65/359 (18%)
zgc:136472	NP_001035331.1	ER_PDI_fam	31..478	CDD:273457	64/355 (18%)
		PDI_a_family	34..122	CDD:239259	23/95 (24%)
		PDI_b_family	147..240	CDD:239279	15/113 (13%)
		PDI_b'_family	252..354	CDD:239280	17/89 (19%)
		PDI_a_PDI_a'_C	375..477	CDD:239293
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592005
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840