Protein Alignment CG5027 and tmx3b

DIOPT Version :9

• Sequence 1: NP_648847.3
• Gene: CG5027 / 39775
• FlyBaseID: FBgn0036579
• Length: 430
• Species: Drosophila melanogaster
• Sequence 2: NP_001039026.1
• Gene: tmx3b / 553250
• ZFINID: ZDB-GENE-060901-5
• Length: 484
• Species: Danio rerio
• Alignment Length: 419
• Identity: 140/419 - (33%)
• Similarity: 234/419 - (55%)
• Gaps: 30/419 - (7%)

  Fly    11 LISALLLTLGSTGLSSKVLELSDRFIDVRHEGQWLVMFYAPWCGYCKKTEPIFALVAQALHATN- 74
            |:|.:||.|        ||:|.|.|.|.|.|..|||.|||||||||||.||::..|...|..:.
Zfish    12 LLSRVLLAL--------VLDLDDSFKDSRMEDVWLVDFYAPWCGYCKKLEPVWEEVGAELSRSGS 68

  Fly    75 -VRVGRLDCTKYPAAAKEFKVRGYPTIMFIKGNMEFTYNGDRGRDELVDYALRMSGPPVQLVTRT 138
             ||||::|.|.|...|.||.|||||||..:||::.:.|.|.|.:|:::::|.|::||.|:.:...
Zfish    69 PVRVGKMDATAYSGMASEFGVRGYPTIKLLKGDLAYNYKGPRTKDDIIEFANRVAGPAVRALPSR 133

  Fly   139 ESVDMLKGSHTIFFIFVGQQEGVVWDTYYAAAEGYQEHGFFYATSEDIAAQHFDFEKLPAVIVYK 203
            :..:.:...|::.|::|| .|..:.:.|...|.....:.:|::.||::..:.....:||:|:|:|
Zfish   134 QMFEHVLKRHSVLFLYVG-GESPLKEKYIEVASELIVYTYFFSASEEVLTEAVVLPELPSVVVFK 197

  Fly   204 EEQHHFYPHGHLAHEMDPNEVNETVFQWVNVERFTLFPKVTRFNIHQLLKTNKYLVLAVVQEDKL 268
            :.....|         |..| :.::..|||.|||..:.::..|.:::|.:|.|.:.:||. :||
Zfish   198 DASFFTY---------DEYE-DGSLSSWVNRERFQSYLQIDGFTLYELGETGKLVAIAVT-DDK- 250

  Fly   269 NQIATHELEFRDMVEGVIRKHRARYHDKFQFGWIGEPSIAHSIILDQLPTPHLIAINSSTQHHFI 333
             ..:.|....:.:::.|..:||.:::..||||.:......:|:|:.::..|.:|.:|:|.:.:|:
Zfish   251 -DQSDHSSRLKGLIQRVATEHREQFNRDFQFGHMSGNDYINSLIMGEVSIPSIIILNTSNEQYFL 314

  Fly   334 PEDDPMQMTPQALHLFLESIRNESAIAYGGDTYFVRLNRALFEVRRALRDMWLGNPVLTTVIFGL 398
            |. :|::...|.|. |..|:.:.||.|||||..|.|:.|..::.|..:..::..:|:|...:|||
Zfish   315 PA-EPVEDLQQMLQ-FFSSVLDGSAPAYGGDGIFQRIKRVAYDARSTIMSVFRSSPLLGCFLFGL 377

  Fly   399 PLGFLSLIMYSIFCGDCLVTEEDPDEDHE 427
            |||.:||:.|.|    |....:|..||.|
Zfish   378 PLGVISLMCYGI----CTAESDDGTEDLE 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5027	NP_648847.3	PDI_a_TMX3	27..128	CDD:239298	51/102 (50%)
		ER_PDI_fam	28..>355	CDD:273457	107/328 (33%)
tmx3b	NP_001039026.1	PDI_a_TMX3	27..123	CDD:239298	47/95 (49%)
		Thioredoxin_6	153..328	CDD:290560	47/189 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591983
Domainoid	1	1.000	84	1.000	Domainoid score	I8201
eggNOG	1	0.900	-	-		E2759_KOG4277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H10381
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330414at33208
OrthoFinder	1	1.000	-	-		FOG0006149
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.750