DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5027 and Tmx4

DIOPT Version :9

Sequence 1:	NP_648847.3	Gene:	CG5027 / 39775	FlyBaseID:	FBgn0036579	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_083424.1	Gene:	Tmx4 / 52837	MGIID:	106558	Length:	335	Species:	Mus musculus

Alignment Length:	182	Identity:	43/182 - (23%)
Similarity:	72/182 - (39%)	Gaps:	25/182 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LISALLLTLGSTGLSSKVLELSDRFID--------VRHEGQWLVMFYAPWCGYCKKTEPIFALVA 67
            |::|.|....:.||....|...:..:.        :..||:|::.||||||..|::|:..:...|
Mouse    10 LLAAWLAAAAAEGLEQAALPAEESRVQPMTASNWTLVMEGEWMLKFYAPWCPSCQQTDSEWETFA 74

  Fly    68 QALHATNVRVGRLDCTKYPAAAKEFKVRGYPTIMFIKGNMEFTYNGDRGRDELVDYALRMSGPPV 132
            :......:.||::|..:.|..:..|.|...|.....|..:...|.|....::|.:|.|......|
Mouse    75 KNGETLQISVGKVDVIQEPGLSGRFFVTTLPAFFHAKDGIFRRYRGPGIYEDLQNYILEKKWQSV 139

  Fly   133 QLVTRTESVDML--KGSHTIFFIFVGQQEGVVWDTYYAAAEGYQEHGFFYAT 182
            :.:|..:|...|  .|...:|.|     .|.:|..          |.:|..|
Mouse   140 EPLTGWKSPASLTMSGMAGLFSI-----SGKIWHL----------HNYFTVT 176

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5027	NP_648847.3	PDI_a_TMX3	27..128	CDD:239298	26/108 (24%)
CG5027	NP_648847.3	ER_PDI_fam	28..>355	CDD:273457	38/165 (23%)
Tmx4	NP_083424.1	Thioredoxin_like	33..133	CDD:294274	24/99 (24%)
Tmx4	NP_083424.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	222..316
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846793
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840