Protein Alignment CG5027 and P4HB

DIOPT Version :9

• Sequence 1: NP_648847.3
• Gene: CG5027 / 39775
• FlyBaseID: FBgn0036579
• Length: 430
• Species: Drosophila melanogaster
• Sequence 2: XP_024306545.1
• Gene: P4HB / 5034
• HGNCID: 8548
• Length: 546
• Species: Homo sapiens
• Alignment Length: 343
• Identity: 81/343 - (23%)
• Similarity: 140/343 - (40%)
• Gaps: 75/343 - (21%)

  Fly    45 LVMFYAPWCGYCKKTEPIFALVAQALHA--TNVRVGRLDCTKYPAAAKEFKVRGYPTIMFIKGNM 107
            ||.|||||||:||...|.:|..|..|.|  :.:|:.::|.|:....|:::.|||||||.|.:
Human    45 LVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFR--- 106

  Fly   108 EFTYNGD----------RGRDELVDYALRMSGPPVQLVTRTESVDMLKGSHTIFFI-FVGQQEGV 161
                |||          |..|::|::..:.:||....:....:.:.|..|..:..| |....|..
Human   107 ----NGDTASPKEYTAGREADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDVESD 167

  Fly   162 VWDTYYAAAEGYQEHGFFYATSEDIAAQHFDFEKLPAVIVYKEEQHHFYPHGHLAHEMDPNEVNE 226
            ....:..|||...:..|...::.|:      |.|                     :::|.:.|
Human   168 SAKQFLQAAEAIDDIPFGITSNSDV------FSK---------------------YQLDKDGV-- 203

  Fly   227 TVFQWVNVERFTLFPKVTRFNIHQLLKTNKY-LVLAVVQE--DKL--NQIATHELEFRDM----V 282
            .:|:..:..|.....:||:.|:...:|.|:. ||:...::  .|:  .:|.||.|.|...    .
Human   204 VLFKKFDEGRNNFEGEVTKENLLDFIKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDY 268

  Fly   283 EGVIRKHRA---RYHDKFQFGWIGEPSIAHSIIL-------DQLPTPHLIAINSSTQHHFIPEDD 337
            :|.:...:.   .:..|..|.:|......:..||       ::.|...||.:... ...:.||.:
Human   269 DGKLSNFKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEE-MTKYKPESE 332

  Fly   338 PMQMTPQAL----HLFLE 351
              ::|.:.:    |.|||
Human   333 --ELTAERITEFCHRFLE 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5027	NP_648847.3	PDI_a_TMX3	27..128	CDD:239298	34/94 (36%)
		ER_PDI_fam	28..>355	CDD:273457	81/343 (24%)
P4HB	XP_024306545.1	YbbN	24..394	CDD:331940	81/343 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156377
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840