DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5027 and pdia8

DIOPT Version :9

Sequence 1:	NP_648847.3	Gene:	CG5027 / 39775	FlyBaseID:	FBgn0036579	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_001003517.1	Gene:	pdia8 / 445123	ZFINID:	ZDB-GENE-040801-20	Length:	493	Species:	Danio rerio

Alignment Length:	201	Identity:	65/201 - (32%)
Similarity:	94/201 - (46%)	Gaps:	42/201 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 NSMWIFGLISALLLTLGSTGLS-SKVLELSDRFIDV---RHEGQWLVMFYAPWCGYCKKTEPIFA 64
            :.|.:.||:..|:.:|.|:... |.||:|:|...|.   .|| ..||.|||||||:|||..|.|.
Zfish     2 DEMILRGLLCILVCSLSSSAREHSDVLKLTDADFDYLAPEHE-TLLVKFYAPWCGHCKKLAPEFE 65

  Fly    65 LVAQALHATNVRVGRLDCTKYPAAAKEFKVRGYPTI-MFIKGNMEFTYNGDRGRDELVDYALRMS 128
            ..|..|..| |.:.::|||......|.:.|.||||: :|..|....:|:|.|..|.:|||..:.:
Zfish    66 SAASRLKGT-VTLAKVDCTANTEICKHYGVNGYPTLKIFRNGQESSSYDGPRSADGIVDYMKKQA 129

  Fly   129 GPP---------------------VQLVTRTES---VDMLKG----------SHTIFFIFVGQQE 159
            ||.                     |.|.:.|:|   .:.|||          :||. .:.:||:.
Zfish   130 GPDSVLLHSELDLEKFINHFDASVVGLFSGTDSSQLAEFLKGASLMRESFRFAHTT-DLQLGQKY 193

  Fly   160 GVVWDT 165
            ||..::
Zfish   194 GVTHES 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5027	NP_648847.3	PDI_a_TMX3	27..128	CDD:239298	43/104 (41%)
CG5027	NP_648847.3	ER_PDI_fam	28..>355	CDD:273457	58/176 (33%)
pdia8	NP_001003517.1	ER_PDI_fam	25..484	CDD:273457	59/178 (33%)
		pdi_dom	30..129	CDD:273454	41/100 (41%)
		PDI_b_ERp57	132..236	CDD:239367	13/69 (19%)
		PDI_b'_ERp72_ERp57	240..353	CDD:239371
		PDI_a_PDI_a'_C	373..476	CDD:239293
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592008
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840