Protein Alignment Tmx3 and p4hb

DIOPT Version :10

• Sequence 1: NP_648847.3
• Gene: Tmx3 / 39775
• FlyBaseID: FBgn0036579
• Length: 430
• Species: Drosophila melanogaster
• Sequence 2: NP_998529.3
• Gene: p4hb / 406673
• ZFINID: ZDB-GENE-080610-1
• Length: 509
• Species: Danio rerio
• Alignment Length: 405
• Identity: 93/405 - (22%)
• Similarity: 166/405 - (40%)
• Gaps: 83/405 - (20%)

  Fly    45 LVMFYAPWCGYCKKTEPIFALVAQALHA--TNVRVGRLDCTKYPAAAKEFKVRGYPTIMFIKGNM 107
            ||.|||||||:||...|.::..|..|.|  :::|:.::|.|:....|:||.|||||||.|.||..
Zfish    43 LVEFYAPWCGHCKALAPEYSKAAGMLKAEGSDIRLAKVDATEESELAQEFGVRGYPTIKFFKGGE 107

  Fly   108 EFT---YNGDRGRDELVDYALRMSGPPVQLVTRTESVDMLKGSHTI----FFIFVGQQEGVVWDT 165
            :..   |:..|..:::|.:..:.:||....:......:.:...:.:    ||..|..::.   ..
Zfish   108 KGNPKEYSAGRQAEDIVSWLKKRTGPAATTLNDVMQAESIIADNEVAVIGFFKDVESEDS---KA 169

  Fly   166 YYAAAEGYQEHGFFYATSEDIAAQHFDFEKLPAVIVYKEEQHHFYPHGHLAHEMDPNEVNETVFQ 230
            :...||...:.. |..||:|.....|:..| .:|:::|:     :..|.  :..|.....|::..
Zfish   170 FIKTAEAVDDIP-FGITSDDSVFAKFEVAK-DSVVLFKK-----FDEGR--NTFDGEVSKESLLN 225

  Fly   231 WVNVERFTLF--------PKVTRFNI--HQLLKTNKYLVLAVVQEDKLNQIATHELEFRDMVEGV 285
            ::...:..|.        ||:...:|  |.|:...|   .|...:||::|       |:...||
Zfish   226 FIKANQLPLVIEFTEQTAPKIFGGDIKSHILMFVPK---AAKDFQDKMDQ-------FKKAAEG- 279

  Fly   286 IRKHRARYHDKFQFGWIGEPSIAHSIIL-------DQLPTPHLIAINSSTQHHFIPEDDPMQMTP 343
                   :..|..|.:|......:..||       ::.|...||.:          |::..:..|
Zfish   280 -------FKGKILFIFIDSDVDDNQRILEFFGLKKEECPVIRLITL----------EEEMTKYKP 327

  Fly   344 QALHLFLESIRNESAIAYGGDTYFVRLNRALFEVRRALRDMWLGNPVLTTVIFGL--------PL 400
            ::..:..|:|     |::  .|.||........:.:.:.:.|..|||  .|:.|.        |.
Zfish   328 ESSEITAENI-----ISF--CTSFVEGTLKPHLMSQDIPEDWDKNPV--KVLVGKNFEEVAFNPA 383

  Fly   401 GFLSLIMYSIFCGDC 415
            ..:.:..|:.:||.|
Zfish   384 NNVFVEFYAPWCGHC 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tmx3	NP_648847.3	PDI_a_TMX3	27..128	CDD:239298	34/87 (39%)
		ER_PDI_fam	28..>355	CDD:273457	78/335 (23%)
p4hb	NP_998529.3	ER_PDI_fam	22..476	CDD:273457	93/405 (23%)