Protein Alignment Tmx3 and pdia7

DIOPT Version :10

• Sequence 1: NP_648847.3
• Gene: Tmx3 / 39775
• FlyBaseID: FBgn0036579
• Length: 430
• Species: Drosophila melanogaster
• Sequence 2: NP_998070.1
• Gene: pdia7 / 405841
• ZFINID: ZDB-GENE-040426-2238
• Length: 488
• Species: Danio rerio
• Alignment Length: 282
• Identity: 80/282 - (28%)
• Similarity: 126/282 - (44%)
• Gaps: 52/282 - (18%)

  Fly    11 LISALLLTLGSTGLSSKVLELSDRFIDVRHEGQ---WLVMFYAPWCGYCKKTEPIFALVAQALHA 72
            :|.|:|....:.|  |.||||.|...| |..|.   .||.|:|||||:|::..|.:...|..|..
Zfish     7 IICAVLTVWLAEG--SDVLELGDSDFD-RSAGMHDTLLVEFFAPWCGHCQRLAPEYEAAATKLKG 68

  Fly    73 TNVRVGRLDCTKYPAAAKEFKVRGYPTI-MFIKGNMEFTYNGDRGRDELVDYALRMSGPPVQLVT 136
            | :.:.::|||......:.|.|.||||: :|..|.....|:|.|..|.:|.|..:.:||
Zfish    69 T-LALAKVDCTVNSETCERFGVNGYPTLKIFRNGEESGAYDGPRTADGIVSYMKKQAGP------ 126

  Fly   137 RTESVDMLKGSHTIFFIFVGQQEGVVWDTYYAAAEGYQEHGFFYATSEDIAAQHFDFEKLPAVIV 201
              .||.:||.:....|:          |.|.|:..     |||  :.|| :||..:|.|..:.:
Zfish   127 --SSVALLKEADLDGFV----------DNYEASVV-----GFF--SGED-SAQLAEFLKASSAL- 170

  Fly   202 YKEEQHHFYPHGHLAHEMDPNEVNETVFQWVNVERFTLF--PKVTRFNIHQLLKTNKYLVLAVVQ 264
              .:.:.|      ||..|   |...:...|:.|...||  |:::......::|..::|.::.:.
Zfish   171 --RDSYRF------AHSTD---VGAGLKYGVDGECVLLFRPPRLSSKFEDNVVKYTEHLSVSSLH 224

  Fly   265 ---EDKLNQIATH-ELEFRDMV 282
               :|.:..:..| .:|.||.|
Zfish   225 KFVKDNILGLCPHMTMENRDTV 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tmx3	NP_648847.3	PDI_a_TMX3	27..128	CDD:239298	38/104 (37%)
		ER_PDI_fam	28..>355	CDD:273457	75/265 (28%)
pdia7	NP_998070.1	ER_PDI_fam	20..483	CDD:273457	76/267 (28%)