DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5027 and txndc5

DIOPT Version :9

Sequence 1:	NP_648847.3	Gene:	CG5027 / 39775	FlyBaseID:	FBgn0036579	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_989186.1	Gene:	txndc5 / 394794	XenbaseID:	XB-GENE-490945	Length:	405	Species:	Xenopus tropicalis

Alignment Length:	196	Identity:	49/196 - (25%)
Similarity:	83/196 - (42%)	Gaps:	39/196 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 SKVLELSDRFIDV------RH--EGQWLVMFYAPWCGYCKKTEPIFALVAQALHATN-VRVGRLD 81
            :||.||.....::      .|  ||...:.|:|||||:||...|.:..:|.....:| :::.::|
Frog   155 AKVPELKQGLYELTAANFKEHIAEGNHFIKFFAPWCGHCKALAPAWEQLAATFQDSNSIKIAKVD 219

  Fly    82 CTKYPAAAKEFKVRGYPTIM-FIKGNMEFTYNGDRGRDELVDYALRMSGP--------------- 130
            ||::.....:.:||||||:: |..|.....|.|.|..|.|.:||.....|
Frog   220 CTQHNGLCSDNQVRGYPTLLWFRNGEKVDQYKGKRDLDSLKEYAESQLKPAEEKKEEEQKEDATP 284

  Fly   131 -----PVQLVTRTESVDMLKGSHTIFFIFVGQQEGVVWDTYYAAAEGYQEHGFFYATSEDIAAQH 190
                 ||.:.::..|:.......|:       ..||.:..:||...|:.::  .....||::.:.
Frog   285 PQVEKPVAVESKVLSLSESNFDQTV-------ATGVSFIKFYAPWCGHCKN--LVPIWEDLSKKE 340

  Fly   191 F 191
            |
Frog   341 F 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5027	NP_648847.3	PDI_a_TMX3	27..128	CDD:239298	36/110 (33%)
CG5027	NP_648847.3	ER_PDI_fam	28..>355	CDD:273457	48/194 (25%)
txndc5	NP_989186.1	PDI_a_ERp46	36..134	CDD:239303
		PDI_a_ERp46	163..262	CDD:239303	30/98 (31%)
		PDI_a_ERp46	296..397	CDD:239303	10/55 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910