Protein Alignment CG5027 and ERp60

DIOPT Version :9

• Sequence 1: NP_648847.3
• Gene: CG5027 / 39775
• FlyBaseID: FBgn0036579
• Length: 430
• Species: Drosophila melanogaster
• Sequence 2: NP_725084.2
• Gene: ERp60 / 36270
• FlyBaseID: FBgn0033663
• Length: 489
• Species: Drosophila melanogaster
• Alignment Length: 475
• Identity: 101/475 - (21%)
• Similarity: 181/475 - (38%)
• Gaps: 116/475 - (24%)

  Fly     6 MWIFGLISALLLTLG----STGLSSKVLELSDRFIDV---RHEGQWLVMFYAPWCGYCKKTEPIF 63
            ||..    |.:|.||    |:|....||||.|.....   :|| ..||||||||||:||:.:|.:
  Fly     2 MWRL----AGVLLLGFIAISSGAEQDVLELGDDDFATTLKQHE-TTLVMFYAPWCGHCKRLKPEY 61

  Fly    64 ALVAQALHATN--VRVGRLDCTKYPAAAKE----FKVRGYPTI-MFIKGNMEFTYNGDRGRDELV 121
            |..|:.:...:  :::.::|||:   |.||    :.|.||||: :|.:..:...|||.|....:.
  Fly    62 AKAAEIVKDDDPPIKLAKVDCTE---AGKETCSKYSVSGYPTLKIFRQDEVSQDYNGPREASGIA 123

  Fly   122 DYALRMSGPPVQLV-TRTESVDMLKGSHTIFFIFVGQQEGVVWDTYYAAAEGYQE-HGFFYATSE 184
            .|.....||..:.| |..|....|....|..|.:....:..:...:...|:..:| :.|.:::.:
  Fly   124 KYMRAQVGPASKTVRTVAELKKFLDTKDTTLFGYFSDSDSKLAKIFLKFADKNREKYRFGHSSEK 188

  Fly   185 DIAAQHFDFEKLPAV-------------------------IVYKEEQHHFYPHGHLAHEMDPNEV 224
            ::..:..:.:|:..:                         ...||..|...  ||...:...:..
  Fly   189 EVLDKQGETDKIVLIRAPHLSNKFESSSIKFEGSSESDLSTFVKENFHGLV--GHRTQDSVKDFQ 251

  Fly   225 NETVFQWVNVERFTLFPKVTRFNIHQLLKTNKYLV----LAVVQEDKLNQIATHELEFRDMVEGV 285
            |..:..:.:|: :...||.|.:..:::||..|..|    .|:..:|...    |||
  Fly   252 NPLITAYYSVD-YQKNPKGTNYWRNRVLKVAKEFVGQINFAIASKDDFQ----HEL--------- 302

  Fly   286 IRKHRARYHDKFQFGWIGEPSIAHSIILDQLPTPHLIAINSSTQHHFIPEDDPMQMTPQALHLFL 350
                     :::.:.::|:             .|.::|.:.....:.:.:    :.:.:.|..|:
  Fly   303 ---------NEYGYDFVGD-------------KPVVLARDEKNLKYALKD----EFSVENLQDFV 341

  Fly   351 ESIRNESAIAYGGDTYFVRLNRALFEVRRA--LRDMWLGNPVLTTVIFGLPLGFLSLIMYSIFCG 413
            |.:.......|.........|.|..:|..|  ..|:.:.|...|.:.|           |:.:||
  Fly   342 EKLLANELEPYIKSEPIPESNDAPVKVAVAKNFDDLVINNGKDTLIEF-----------YAPWCG 395

  Fly   414 DCL--------VTEEDPDED 425
            .|.        :.|:..|||
  Fly   396 HCKKLSPIYEELAEKLQDED 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5027	NP_648847.3	PDI_a_TMX3	27..128	CDD:239298	39/110 (35%)
		ER_PDI_fam	28..>355	CDD:273457	76/367 (21%)
ERp60	NP_725084.2	ER_PDI_fam	23..479	CDD:273457	93/450 (21%)
		PDI_a_PDIR	23..126	CDD:239295	38/106 (36%)
		PDI_b_ERp57	133..235	CDD:239367	12/101 (12%)
		PDI_b'_ERp72_ERp57	239..345	CDD:239371	22/147 (15%)
		PDI_a_PDI_a'_C	365..467	CDD:239293	14/62 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463720
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840